Brief Information of the Compound and Protein
Compound Name
(5-fluoro-4-methyl-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
    Show/Hide
PubChem ID
CID: 11594278
SID: 16696875
Canonical SMILES
CN1CCN(CC1)C(=O)c1nc2ccc(F)c(C)c2[nH]1
    Show/Hide
Compound Formula C14H17FN4O
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
Kd = 15.85 nM
   TI
   LI
   LO
   TS
2
Ki = 7 nM
   TI
   LI
   LO
   TS