Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-cyano-3-[[(2R,5S)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
    Show/Hide
 PubChem ID
CID: 11086114
SID: 16156741
Canonical SMILES
C\N=C(\NC[C@H]1CC[C@H](O1)c1c[nH]cn1)NC#N
    Show/Hide
Compound Formula C11H16N6O
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 7943.28 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 7585.78 nM
   TI
   LI
   LO
   TS
2
EC50 = 7943.28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 8128.31 nM