General Information of the Compound
| Compound ID |
CP0076121
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| Compound Name |
13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene
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| Synonyms |
2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz(b,f)(1,4)oxazepine
2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine
2-Chloro-11-(4-methylpiperazino)dibenzo(b,f)(1,4)oxazepine
2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine
8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,5]benzoxazepine
CL 62362
CL-62362
CL-71,563
Cloxazepine
Dibenzacepin
Dibenzoazepine
HF 3170
HF3170
Hydrofluoride 3170
LW 3170
Lossapina
Lossapina [DCIT]
Loxapac (TN)
Loxapin
Loxapina
Loxapina [INN-Spanish]
Loxapine
Loxapine (USAN/INN)
Loxapine [USAN:BAN:INN]
Loxapine [USAN:INN:BAN]
Loxapinsuccinate
Loxapinum
Loxapinum [INN-Latin]
Loxepine
Loxitane (TN)
Loxitane IM
Oxilapine
S 805
S-805;SUM-3170
SUM 3170
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| Structure |
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| Formula |
C18H18ClN3O
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| Molecular Weight |
327.815
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| Canonical SMILES |
CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12
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| InChI |
InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3
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| InChIKey |
XJGVXQDUIWGIRW-UHFFFAOYSA-N
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| CAS |
1977-10-2
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
Protein ID: PT01005, D(2) dopamine receptor
Protein ID: PT01161, D(4) dopamine receptor
Protein ID: PT01711, Histamine H4 receptor
Protein ID: PT01310, Muscarinic acetylcholine receptor M1
Clinical Information about the Compound