Brief Information of the Compound and Protein
Compound Name
13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene
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PubChem ID
CID: 3964
SID: 14875092
Canonical SMILES
CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12
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Compound Formula C18H18ClN3O
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
EC50 = 218.78 nM
   TI
   LI
   LO
   TS
2
Ki = 4570.88 nM
   TI
   LI
   LO
   TS