General Information of the Compound
| Compound ID |
CP0259827
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| Compound Name |
4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
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| Structure |
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| Formula |
C15H19N5
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| Molecular Weight |
269.352
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| Canonical SMILES |
CN1CCN(CC1)c1cc(nc(N)n1)-c1ccccc1
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| InChI |
InChI=1S/C15H19N5/c1-19-7-9-20(10-8-19)14-11-13(17-15(16)18-14)12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3,(H2,16,17,18)
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| InChIKey |
NIJGWJIOMPHDBP-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02227, 5-hydroxytryptamine receptor 3A
Protein ID: PT02519, Histamine H4 receptor
Protein ID: PT01711, Histamine H4 receptor
Cell-based Assay