Brief Information of the Compound and Protein
Compound Name
8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(isoclothiapine)
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PubChem ID
CID: 9928073
SID: 14900481
Canonical SMILES
CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Sc2ccccc12
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Compound Formula C18H18ClN3S
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 2041.74 nM
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   LI
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