Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S,4S)-1-(2-amino-6-cyclopentylpyrimidin-4-yl)-4-(methylamino)pyrrolidin-3-ol
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 PubChem ID
CID: 24994636
SID: 56336656
Canonical SMILES
CN[C@H]1CN(C[C@@H]1O)c1cc(nc(N)n1)C1CCCC1
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Compound Formula C14H23N5O
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  2
1
Kd = 10 nM
   TI
   LI
   LO
   TS
2
Ki = 30 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 > 10000 nM