Brief Information of the Compound and Protein
Compound Name
(4-chloro-6-methyl-1H-benzoimidazol-2-yl)(4-methylpiperazin-1-yl)methanone
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PubChem ID
CID: 11687917
SID: 16792219
Canonical SMILES
CN1CCN(CC1)C(=O)c1nc2cc(C)cc(Cl)c2[nH]1
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Compound Formula C14H17ClN4O
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
Kd = 125.89 nM
   TI
   LI
   LO
   TS
2
Ki = 23 nM
   TI
   LI
   LO
   TS