Brief Information of the Compound and Protein
Compound Name
4-[(3S)-3-aminopyrrolidin-1-yl]-6-cyclopentylpyrimidin-2-amine
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PubChem ID
CID: 90655028
Canonical SMILES
N[C@H]1CCN(C1)c1cc(nc(N)n1)C1CCCC1
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Compound Formula C13H21N5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 36 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 > 10000 nM