Brief Information of the Compound and Protein
Compound Name
N-(2-bicyclo[2.2.1]heptanyl)-5-[(3S)-3-(methylamino)pyrrolidin-1-yl]pyridazin-3-amine
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PubChem ID
CID: 58227086
Canonical SMILES
CN[C@H]1CCN(C1)c1cnnc(NC2CC3CCC2C3)c1
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Compound Formula C16H25N5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Kd = 7.943 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5 nM