Brief Information of the Compound and Protein
Compound Name
(+/-)-5-fluoro-2-(4-(3-(hexahydropyrrolo[3,4-b]pyrrol-5(1H)-yl)propoxy)-2-methylphenyl)-4-methyl-1H-benzo[d]imidazole
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PubChem ID
CID: 46890627
Canonical SMILES
Cc1cc(OCCCN2CC3CCNC3C2)ccc1-c1nc2ccc(F)c(C)c2[nH]1
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Compound Formula C24H29FN4O
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Kd = 12.59 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 26 nM