Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(4-methylpiperazin-1-yl)-2-N-(2-methylpropyl)pyrimidine-2,4-diamine
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 PubChem ID
CID: 53233801
SID: 124342620
Canonical SMILES
CC(C)CNc1nc(N)cc(n1)N1CCN(C)CC1
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Compound Formula C13H24N6
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 86 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 15 nM