Brief Information of the Compound and Protein
Compound Name
4-[(3aS,6aR)-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl]-6-cyclopentylpyrimidin-2-amine
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PubChem ID
CID: 90655029
Canonical SMILES
Nc1nc(cc(n1)N1C[C@@H]2CNC[C@@H]2C1)C1CCCC1
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Compound Formula C15H23N5
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  1
1
Ki = 328 nM
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