Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
    Show/Hide
 PubChem ID
CID: 3692
SID: 15321889
Canonical SMILES
NC(=N)SCCc1cnc[nH]1
    Show/Hide
Compound Formula C6H10N4S
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 1.6 nM
   TI
   LI
   LO
   TS
2
Ki = 6.31 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 6.31 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 12.59 nM
   TI
   LI
   LO
   TS
2
Ki = 3.6 nM
   TI
   LI
   LO
   TS
3
Ki = 6.31 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 51 nM