Brief Information of the Compound and Protein
Compound Name
7-chloro-3-fluoro-11-(4-methylpiperazin-1-yl)-dibenzo[b,f][1,4]oxazepine
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PubChem ID
CID: 11846465
SID: 17159230
Canonical SMILES
CN1CCN(C2=Nc3ccc(Cl)cc3Oc3cc(F)ccc32)CC1
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Compound Formula C18H17ClFN3O
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC Homo sapiens (Human)  2
1
EC50 = 38.9 nM
   TI
   LI
   LO
   TS
2
Ki = 38.9 nM
   TI
   LI
   LO
   TS