Brief Information of the Compound and Protein
Compound Name
2-[3-(1H-imidazol-5-yl)propyl]-1-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
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PubChem ID
CID: 41376
SID: 15396446
Canonical SMILES
Cc1nc[nH]c1CSCCN=C(N)NCCCc1cnc[nH]1
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Compound Formula C14H23N7S
Compound Structure
Protein Name
Histamine H4 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 25.12 nM
   TI
   LI
   LO
   TS
CL000074 SK-N-MC Homo sapiens (Human)  1
1
EC50 = 25.12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 12.3 nM