Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-5-fluoro-4-methyl-2-(2-methyl-4-(3-(3-methyl-3,6-diazabicyclo[3.1.0]hexan-6-yl)propoxy)phenyl)-1H-benzo[d]imidazole
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 PubChem ID
CID: 46890019
Canonical SMILES
CN1CC2C(C1)N2CCCOc1ccc(-c2nc3ccc(F)c(C)c3[nH]2)c(C)c1
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Compound Formula C23H27FN4O
Compound Structure
Protein Name
 Protein Info 
Histamine H4 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
Q9H3N8
Gene Name
HRH4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000074 SK-N-MC
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 710 nM
   TI
   LI
   LO
   TS
2
Kd = 66.07 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 77 nM