General Information of the Cell Line
Cell Line ID
CL000148
Cell Line Name
Huh-7
Synonyms
HuH-7
HUH-7
HuH7
Huh7
HUH7
HUH7.0
JTC-39
Japanese Tissue Culture-39
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0336
Tissue Information
Liver
Disease
Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00894, Androgen receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0858705
 Compound Info 
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-propylpyridine-3-carboxylate
   Show/Hide
C18H18ClFN2O2
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0645863
 Compound Info 
(R)-Methyl 2-((1H-Tetrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
   Show/Hide
C17H14ClFN6O2
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0683120
 Compound Info 
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,4-dihydro-2,6-dimethylpyridine-3-carboxylate
   Show/Hide
C16H14ClFN2O2
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0805098
 Compound Info 
Methyl 4-(2-Chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-propylpyridine-3-carboxylate
   Show/Hide
C18H19ClN2O2
  1
1
IC50 = 300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0675469
 Compound Info 
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-6-methyl-2-(trifluoromethyl)-1,4-dihydropyridine-3-carboxylate
   Show/Hide
C16H11ClF4N2O2
  1
1
IC50 = 800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0675470
 Compound Info 
Methyl 2-((1H-Pyrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
   Show/Hide
C19H16ClFN4O2
  1
1
IC50 = 800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0906869
 Compound Info 
Methyl 2-Butyl-4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methylpyridine-3-carboxylate
   Show/Hide
C19H21ClN2O2
  1
1
IC50 = 900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0790986
 Compound Info 
Methyl 2-((1H-Tetrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
   Show/Hide
C17H14ClFN6O2
  1
1
IC50 = 2700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0645725
 Compound Info 
Methyl 2-((1H-Imidazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
   Show/Hide
C19H16ClFN4O2
  1
1
IC50 = 3900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0645727
 Compound Info 
Methyl 2-((1H-1,2,4-Triazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
   Show/Hide
C18H15ClFN5O2
  1
1
IC50 = 4600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0072958
 Compound Info 
6-[(2R,5R)-2-methyl-5-phenylmorpholin-4-yl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
   Show/Hide
C18H19N3O3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0086230
 Compound Info 
6-[(3R)-3-phenylmorpholin-4-yl]-4H-1,4-benzoxazin-3-one
   Show/Hide
C18H18N2O3
  1
1
IC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT01286, Bile acid receptor
 Protein Info 
Protein ID: PT00295, Capsid protein
 Protein Info 
Protein ID: PT02581, Cytidine deaminase
 Protein Info 
Protein ID: PT01343, Fibroblast growth factor receptor 4
 Protein Info 
Protein ID: PT00026, Genome polyprotein
 Protein Info 
Protein ID: PT00967, Glucocorticoid receptor
 Protein Info 
Protein ID: PT06765, Liver-expressed antimicrobial peptide 1
 Protein Info 
Protein ID: PT01154, Mineralocorticoid receptor
 Protein Info 
Protein ID: PT01631, Mineralocorticoid receptor
 Protein Info 
Protein ID: PT00149, Nonstructural protein 5A
 Protein Info 
Protein ID: PT01555, Oxysterols receptor LXR-alpha
 Protein Info 
Protein ID: PT01887, Oxysterols receptor LXR-beta
 Protein Info 
Protein ID: PT00910, Peroxisome proliferator-activated receptor alpha
 Protein Info 
Protein ID: PT00909, Peroxisome proliferator-activated receptor delta
 Protein Info 
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
 Protein Info 
Protein ID: PT01172, Progesterone receptor
 Protein Info 
Protein ID: PT00064, Protease
 Protein Info 
Protein ID: PT07525, RNA-binding protein FXR2
 Protein Info 
Protein ID: PT00013, RNA-directed RNA polymerase
 Protein Info 
Protein ID: PT06441, Scavenger receptor class B member 1
 Protein Info 
Protein ID: PT02160, Toll-like receptor 7
 Protein Info 
Protein ID: PT04436, UMP-CMP kinase
 Protein Info 
Protein ID: PT06194, Uridine-cytidine kinase 1
 Protein Info 
Protein ID: PT02378, Vitamin D3 receptor
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0007893
 Compound Info 
4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
   Show/Hide
 C23H27N7O3S2  1
1
IC50 = 1720 nM
   TI
   LI
   LO
   TS
CP0029881
 Compound Info 
ABT-267
   Show/Hide
 C50H67N7O8  1
1
CC50 > 1 nM
   TI
   LI
   LO
   TS
CP0032115
 Compound Info 
(2R,3aR,10Z,11aS,12aR,14aR)-N-(cyclopropylsulfonyl)-2-({7-methoxy-8-methyl-2-[4-(1-methylethyl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-5-methyl-4,14-dioxo-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydrocyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-12a(1H)-carboxamide
   Show/Hide
 C38H47N5O7S2  1
1
CC50 = 47000 nM
   TI
   LI
   LO
   TS
CP0047412
 Compound Info 
2-(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-1H-pyrazol-3-yl)-5-tert-butyl-1,3,4-thiadiazole
   Show/Hide
 C24H21BrClN7S  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0141193
 Compound Info 
2-amino-1-[3-(1,3-benzodioxol-5-ylamino)-2-phenyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]ethanone
   Show/Hide
 C21H21N5O3  1
1
TC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0149294
 Compound Info 
(1S,2S,3R,4R)-3-[[5-cyano-2-[4-[4-(dimethylamino)piperidin-1-yl]-2-(2-methylpropoxy)anilino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide
   Show/Hide
 C30H40N8O2  1
1
IC50 = 237 nM
   TI
   LI
   LO
   TS
CP0189862
 Compound Info 
US9266883, 101
   Show/Hide
 C25H29N7O5  1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CP0202740
 Compound Info 
4-[(2S)-2-(1,6-dimethylbenzimidazol-2-yl)-2-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]ethyl]benzamide
   Show/Hide
 C33H29N5O4  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0225649
 Compound Info 
2-amino-1-[3-(4-fluoroanilino)-2-(4-fluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
   Show/Hide
 C22H23F2N5O  1
1
TC50 > 12000 nM
   TI
   LI
   LO
   TS
CP0231014
 Compound Info 
US9266883, 201
   Show/Hide
 C17H15N5O2  1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0239675
 Compound Info 
3-[(1S)-1-(1,6-dimethylbenzimidazol-2-yl)-2-[1-(2-methylpropanoyl)piperidin-4-yl]ethyl]-1-[4-(4-fluorophenoxy)phenyl]imidazolidine-2,4-dione
   Show/Hide
 C35H38FN5O4  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0259227
 Compound Info 
5-[9-[3-(3,5-difluorophenyl)sulfanylpropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
   Show/Hide
 C24H23F2N3OS  1
1
CC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0303879
 Compound Info 
4-[1-[2,4-dimethyl-5-(6-pyrrolidin-1-yl-3H-imidazo[4,5-c]pyridin-2-yl)benzoyl]piperidin-4-yl]benzonitrile
   Show/Hide
 C31H32N6O  1
1
CC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0356387
 Compound Info 
4-[(2S)-2-(1,6-dimethylbenzimidazol-2-yl)-2-[2,5-dioxo-3-(4-phenoxyphenyl)imidazolidin-1-yl]ethyl]benzonitrile
   Show/Hide
 C33H27N5O3  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0357117
 Compound Info 
3-[(1S)-1-(1-cyclopropyl-6-methylbenzimidazol-2-yl)-2-[1-(2-methylpropanoyl)piperidin-4-yl]ethyl]-1-[4-(4-fluorophenoxy)phenyl]imidazolidine-2,4-dione
   Show/Hide
 C37H40FN5O4  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0362936
 Compound Info 
BCX-4430
   Show/Hide
 C11H15N5O3  1
1
CC50 > 89000 nM
   TI
   LI
   LO
   TS
CP0380881
 Compound Info 
19-cyclohexyl-10-(3,8-diazabicyclo[3.2.1]octane-8-carbonyl)-N-(dimethylsulfamoyl)-5-methoxy-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
   Show/Hide
 C35H43N5O5S  1
1
CC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0382935
 Compound Info 
3-(4-methylpiperazin-1-yl)-N-[(1S)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-[3-(4-methylpiperazin-1-yl)propanoylamino]-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]propanamide
   Show/Hide
 C58H68N10O4S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0395302
 Compound Info 
19-cyclohexyl-N-(dimethylsulfamoyl)-5-methoxy-10-(3-methyl-3,6-diazabicyclo[3.1.1]heptane-6-carbonyl)-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
   Show/Hide
 C35H43N5O5S  1
1
CC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0402272
 Compound Info 
methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)pentanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-oxopentan-2-yl]carbamate
   Show/Hide
 C40H48N6O6S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0402273
 Compound Info 
N-[(2R)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(cyclopropanecarbonylamino)-3,3-dimethylbutanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]cyclopropanecarboxamide
   Show/Hide
 C46H56N6O4S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0402274
 Compound Info 
N-[(2R)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(cyclopropanecarbonylamino)-4-methylpentanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]cyclopropanecarboxamide
   Show/Hide
 C46H56N6O4S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0402275
 Compound Info 
N-[(1R)-2-oxo-1-phenyl-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-phenyl-2-(thiophene-3-carbonylamino)acetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]ethyl]thiophene-3-carboxamide
   Show/Hide
 C52H44N6O4S4  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0402430
 Compound Info 
methyl N-[(2S)-1-[(2S)-2-[[4-[(2R,5R)-5-[4-[[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]phenyl]-1-(4-triethylsilylphenyl)pyrrolidin-2-yl]phenyl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
   Show/Hide
 C52H73N7O8Si  1
1
CC50 > 1 nM
   TI
   LI
   LO
   TS
CP0406404
 Compound Info 
19-cyclohexyl-10-[(3R,5S)-3,5-dimethylpiperazine-1-carbonyl]-N-(dimethylsulfamoyl)-5-methoxy-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
   Show/Hide
 C35H45N5O5S  1
1
CC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0421076
 Compound Info 
N-[(1S)-2-oxo-1-phenyl-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-phenyl-2-(thiophene-2-carbonylamino)acetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]ethyl]thiophene-2-carboxamide
   Show/Hide
 C52H44N6O4S4  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0426216
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(morpholine-4-carbonylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]morpholine-4-carboxamide
   Show/Hide
 C52H54N8O6S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0431959
 Compound Info 
19-cyclohexyl-N-(dimethylsulfamoyl)-10-(3-hydroxy-3-propan-2-ylazetidine-1-carbonyl)-5-methoxy-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
   Show/Hide
 C35H44N4O6S  1
1
CC50 = 6500 nM
   TI
   LI
   LO
   TS
CP0434254
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(furan-3-carbonylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]furan-3-carboxamide
   Show/Hide
 C52H44N6O6S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0434255
 Compound Info 
N-[(1R)-2-oxo-1-phenyl-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-phenyl-2-[(2-phenylacetyl)amino]acetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]ethyl]-2-phenylacetamide
   Show/Hide
 C58H52N6O4S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0434257
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-acetamido-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]acetamide
   Show/Hide
 C46H44N6O4S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0434315
 Compound Info 
N-[(2R)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(cyclopropanecarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]cyclopropanecarboxamide
   Show/Hide
 C44H52N6O4S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0440013
 Compound Info 
N-[(2R)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(cyclopropanecarbonylamino)hexanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-oxohexan-2-yl]cyclopropanecarboxamide
   Show/Hide
 C46H56N6O4S2  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0451035
 Compound Info 
methyl N-[(2S)-1-[(2S)-2-[[4-[(2S,5S)-5-[4-[[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]phenyl]-1-(4-trimethylsilylphenyl)pyrrolidin-2-yl]phenyl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
   Show/Hide
 C49H67N7O8Si  1
1
CC50 > 1 nM
   TI
   LI
   LO
   TS
CP0451664
 Compound Info 
US9266883, 80
   Show/Hide
 C20H22N6O4  1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
CP0451666
 Compound Info 
N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[[methyl(2-methylpropanoyl)amino]methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
   Show/Hide
 C25H31N7O4  1
1
IC50 = 89 nM
   TI
   LI
   LO
   TS
CP0469227
 Compound Info 
19-cyclohexyl-N-(dimethylsulfamoyl)-5-methoxy-10-[(3R,5S)-3,4,5-trimethylpiperazine-1-carbonyl]-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
   Show/Hide
 C36H47N5O5S  1
1
CC50 = 8000 nM
   TI
   LI
   LO
   TS
CP0469229
 Compound Info 
19-cyclohexyl-N-(dimethylsulfamoyl)-10-(3-hydroxy-3-methylazetidine-1-carbonyl)-5-methoxy-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
   Show/Hide
 C33H40N4O6S  1
1
CC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0482293
 Compound Info 
3-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-1-(6-formylpyridin-2-yl)-1-methylurea
   Show/Hide
 C17H18N6O3  1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS
CP0487397
 Compound Info 
19-cyclohexyl-N-(dimethylsulfamoyl)-5-methoxy-10-(8-oxa-3-azabicyclo[3.2.1]octane-3-carbonyl)-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
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 C35H42N4O6S  1
1
CC50 > 10000 nM
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CP0530500
 Compound Info 
3-[(1S)-1-(1-cyclopropyl-6-methylbenzimidazol-2-yl)-2-[1-(2-methylpropanoyl)piperidin-4-yl]ethyl]-1-[4-(4-methoxyphenoxy)phenyl]imidazolidine-2,4-dione
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 C38H43N5O5  1
1
IC50 > 100000 nM
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CP0535190
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(cyclopropanecarbonylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]cyclopropanecarboxamide
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 C50H48N6O4S2  1
1
CC50 > 50000 nM
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CP0544370
 Compound Info 
US9266883, 249
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 C24H28N6O4  1
1
IC50 = 53 nM
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CP0544371
 Compound Info 
US9266883, 266
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 C27H33N7O4  1
1
IC50 = 193 nM
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CP0547108
 Compound Info 
methyl N-[(2S)-1-[(2S)-2-[[4-[(2S,5R)-5-[4-[[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidine-2-carbonyl]amino]phenyl]-1-(4-trimethylsilylphenyl)pyrrolidin-2-yl]phenyl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
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 C49H67N7O8Si  1
1
CC50 > 1 nM
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CP0547373
 Compound Info 
19-cyclohexyl-10-[4-(dimethylcarbamoyl)piperazine-1-carbonyl]-N-(dimethylsulfamoyl)-5-methoxy-12-azapentacyclo[10.7.0.02,7.08,10.013,18]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide
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 C36H46N6O6S  1
1
CC50 > 10000 nM
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CP0547800
 Compound Info 
(3S,5S)-8-(4-fluorophenyl)-3-(hydroxymethyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
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 C22H23FN2O6S  1
1
CC50 > 3000 nM
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CP0547985
 Compound Info 
methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)propanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamate
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 C36H40N6O6S2  1
1
CC50 > 50000 nM
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CP0547986
 Compound Info 
N-[(1R)-2-oxo-1-phenyl-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-phenyl-2-(pyridine-4-carbonylamino)acetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]ethyl]pyridine-4-carboxamide
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 C54H46N8O4S2  1
1
CC50 > 50000 nM
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CP0549481
 Compound Info 
ethyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(ethoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
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 C42H52N6O6S2  1
1
CC50 > 50000 nM
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CP0549594
 Compound Info 
6-[[acetyl(methyl)amino]methyl]-N-[5-cyano-4-(propan-2-ylamino)pyridin-2-yl]-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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 C23H27N7O3  1
1
IC50 = 21 nM
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CP0550939
 Compound Info 
N-[(1S)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-benzamido-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]benzamide
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 C56H48N6O4S2  1
1
CC50 > 50000 nM
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CP0550941
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(2,2-dimethylpropanoylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]-2,2-dimethylpropanamide
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 C52H56N6O4S2  1
1
CC50 > 50000 nM
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CP0551889
 Compound Info 
3-[(1S)-1-(1,6-dimethylbenzimidazol-2-yl)-2-phenylethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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 C32H28N4O3  1
1
IC50 > 100000 nM
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CP0553341
 Compound Info 
6-[[acetyl(methyl)amino]methyl]-N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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 C23H27N7O4  1
1
IC50 = 141 nM
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CP0556557
 Compound Info 
N-[(1R)-2-oxo-1-phenyl-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-phenyl-2-(3-pyrrol-1-ylpropanoylamino)acetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]ethyl]-3-pyrrol-1-ylpropanamide
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 C56H54N8O4S2  1
1
CC50 > 50000 nM
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CP0556562
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(furan-3-carbonylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]furan-3-carboxamide
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 C52H44N6O6S2  1
1
CC50 > 50000 nM
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CP0556563
 Compound Info 
N-[(1R)-2-oxo-1-phenyl-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-phenyl-2-(pyridine-3-carbonylamino)acetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]ethyl]pyridine-3-carboxamide
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 C54H46N8O4S2  1
1
CC50 > 50000 nM
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CP0561763
 Compound Info 
methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)hexanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamate
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 C42H52N6O6S2  1
1
CC50 > 50000 nM
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CP0561768
 Compound Info 
N-[(1R)-2-oxo-1-phenyl-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-phenyl-2-(3-pyrrolidin-1-ylpropanoylamino)acetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]ethyl]-3-pyrrolidin-1-ylpropanamide
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 C56H62N8O4S2  1
1
CC50 > 50000 nM
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CP0561770
 Compound Info 
3-(dimethylamino)-N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-[3-(dimethylamino)propanoylamino]-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]propanamide
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 C52H58N8O4S2  1
1
CC50 > 50000 nM
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CP0562017
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(morpholine-4-carbonylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]morpholine-4-carboxamide
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 C52H54N8O6S2  1
1
CC50 > 50000 nM
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CP0562018
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(cyclohexanecarbonylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]cyclohexanecarboxamide
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 C56H60N6O4S2  1
1
CC50 > 50000 nM
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CP0563256
 Compound Info 
methyl N-[(2S)-1-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)butanoyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-1-oxobutan-2-yl]carbamate
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 C38H44N6O6S2  1
1
CC50 > 50000 nM
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CP0563259
 Compound Info 
N-[(1R)-2-oxo-1-phenyl-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-phenyl-2-(pyrrolidine-1-carbonylamino)acetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]ethyl]pyrrolidine-1-carboxamide
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 C52H54N8O4S2  1
1
CC50 > 50000 nM
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CP0572121
 Compound Info 
N-(5-cyano-4-propan-2-yloxypyridin-2-yl)-7-formyl-6-[[methyl(methylsulfonyl)amino]methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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 C22H26N6O5S  1
1
IC50 = 604 nM
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CP0575367
 Compound Info 
3-(diethylamino)-N-[(1S)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-[3-(diethylamino)propanoylamino]-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]propanamide
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 C56H66N8O4S2  1
1
CC50 > 50000 nM
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CP0575368
 Compound Info 
N-[(1S)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(furan-2-carbonylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]furan-2-carboxamide
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 C52H44N6O6S2  1
1
CC50 > 50000 nM
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CP0575372
 Compound Info 
N-[(1R)-2-[(2S)-2-[5-[4-[4-[2-[(2S)-1-[(2R)-2-(furan-2-carbonylamino)-2-phenylacetyl]pyrrolidin-2-yl]-1,3-thiazol-5-yl]phenyl]phenyl]-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxo-1-phenylethyl]furan-2-carboxamide
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 C52H44N6O6S2  1
1
CC50 > 50000 nM
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CP0644004
 Compound Info 
VELPATASVIR
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 C49H54N8O8  1
1
CC50 > 44400 nM
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CP0774360
 Compound Info 
4-amino-1-((1S,3R,5R)-4,4-difluoro-1-(hydroxymethyl)-2,6-dioxabicyclo[3.2.0]heptan-3-yl)pyrimidin-2(1H)-one
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 C10H11F2N3O4  1
1
CC50 > 50000 nM
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CP0774603
 Compound Info 
4-amino-1-((1S,3R,4S,5R)-4-fluoro-1-(hydroxymethyl)-2,6-dioxabicyclo[3.2.0]heptan-3-yl)pyrimidin-2(1H)-one
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 C10H12FN3O4  1
1
CC50 > 50000 nM
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Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Liver)
Cell Line Name Organism Disease
HLF
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-7-Lunet
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-7.5
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-5-2
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
PLC/PRF/5
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Hep 3B2.1-7
 Cell Line Info 
Homo sapiens (Human) Childhood hepatocellular carcinoma
VACO 241
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
LM
 Cell Line Info 
Homo sapiens (Human) Extrarenal rhabdoid tumor of the liver
GTL-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
MKN45
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
NCI-N87
 Cell Line Info 
Homo sapiens (Human) Gastric tubular adenocarcinoma
Hep-G2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2/C3A
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
CellSensor ARE-bla Hep G2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2 VA-13
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepDES19
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
DPX2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2/2.2.15
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepAD38
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepG2-Lucia AhR
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepG2-hNTCP
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HCCC-9810
 Cell Line Info 
Homo sapiens (Human) Intrahepatic cholangiocarcinoma
SU.86.86
 Cell Line Info 
Homo sapiens (Human) Pancreatic adenocarcinoma
Capan-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
Hepa-1c1c7
 Cell Line Info 
Mus musculus (Mouse) Hepatocellular carcinoma of the mouse
H5
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H4-II-E
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H4-II-E-C3
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
McA-RH7777
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H2.35
 Cell Line Info 
Mus musculus (Mouse) -