Brief Information of the Cell Line and Protein
Cell Line ID: CL000148 , Huh-7
Synonyms
HuH-7
HUH-7
HuH7
Huh7
HUH7
HUH7.0
JTC-39
Japanese Tissue Culture-39
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0336
Protein ID: PT00915 , Peroxisome proliferator-activated receptor gamma
Gene Name PPARG
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P37231
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000148  Protein ID: PT00915
 
Compound ID Compound Name Compound Formula
CP0099056
(5-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPOXY}-1H-INDOL-1-YL)ACETIC ACID
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C33H31NO5
 1
1
EC50 = 70 nM
   TI
   LI
   LO
   TS
CP0159334
2-(5-(3-(4-(4-fluorobenzoyl)-2-propylphenoxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C29H28FNO5
 1
1
EC50 = 160 nM
   TI
   LI
   LO
   TS
CP0500572
2-(1-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propyl)-1H-indol-4-yloxy)-2-methylpropanoic acid
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C35H35NO5
 1
1
EC50 = 210 nM
   TI
   LI
   LO
   TS
CP0005387
Avandamet
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C18H19N3O3S
 1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS
CP0172622
2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propoxy)-1H-indol-1-yl)acetic acid
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C24H23F3N2O5
 1
1
EC50 = 230 nM
   TI
   LI
   LO
   TS
CP0210067
2-{5-[4-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)butoxy]-1H-indol-1-yl}ethanoic acid
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C25H25F3N2O5
 1
1
EC50 = 280 nM
   TI
   LI
   LO
   TS
CP0179987
2-{5-[3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy)propoxy]-indol-1-yl}ethanoic acid
   Show/Hide
C29H28N2O5
 1
1
EC50 = 290 nM
   TI
   LI
   LO
   TS
CP0280350
2-{4-[3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy)propoxy]-indol-1-yl}ethanoic acid
   Show/Hide
C29H28N2O5
 1
1
EC50 = 430 nM
   TI
   LI
   LO
   TS
CP0394241
2-(1-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propyl)-1H-indol-6-yloxy)-2-methylpropanoic acid
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C35H35NO5
 1
1
EC50 = 470 nM
   TI
   LI
   LO
   TS
CP0408693
2-(1-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propyl)-1H-indol-5-yloxy)-2-methylpropanoic acid
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C35H35NO5
 1
1
EC50 = 650 nM
   TI
   LI
   LO
   TS
CP0485780
2-(5-(2-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)ethoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C23H21F3N2O5
 1
1
EC50 = 690 nM
   TI
   LI
   LO
   TS
CP0225560
7-propyl-6-[3-[1-(2H-tetrazol-5-ylmethyl)indol-5-yl]oxypropoxy]-3-(trifluoromethyl)-1,2-benzoxazole
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C24H23F3N6O3
 1
1
EC50 = 898 nM
   TI
   LI
   LO
   TS
CP0486652
3-{5-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}propanoic acid
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C25H25F3N2O5
 1
1
EC50 = 1200 nM
   TI
   LI
   LO
   TS
CP0254793
2-{6-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}ethanoic acid
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C24H23F3N2O5
 1
1
EC50 = 1350 nM
   TI
   LI
   LO
   TS
CP0255138
2-{5-[5-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)pentyloxy]-1H-indol-1-yl}ethanoic acid
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C26H27F3N2O5
 1
1
EC50 = 1490 nM
   TI
   LI
   LO
   TS
CP0186632
2-(5-(3-(6-benzoylnaphthalen-2-yloxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C30H25NO5
 1
1
EC50 = 1630 nM
   TI
   LI
   LO
   TS
CP0225561
2-{5-[3-(7-propyl-1H-indol-6-yl)propoxy]indol-1-yl}ethanoic acid
   Show/Hide
C24H26N2O4
 1
1
EC50 = 1810 nM
   TI
   LI
   LO
   TS
CP0221009
2-{4-[4-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)butoxy]-1H-indol-1-yl}ethanoic acid
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C25H25F3N2O5
 1
1
EC50 = 1981 nM
   TI
   LI
   LO
   TS
CP0159276
2-(5-(3-(4-(4-fluorobenzoyl)phenoxy)propoxy)-1H-indol-1-yl)acetic acid
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C26H22FNO5
 1
1
EC50 = 2160 nM
   TI
   LI
   LO
   TS
CP0180104
3-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}propanoic acid
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C25H25F3N2O5
 1
1
EC50 = 2190 nM
   TI
   LI
   LO
   TS
CP0408695
2-(1-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propyl)-1H-indol-5-yloxy)acetic acid
   Show/Hide
C33H31NO5
 1
1
EC50 = 2210 nM
   TI
   LI
   LO
   TS
CP0099080
2-(4-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C33H31NO5
 1
1
EC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0192465
2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}ethanoic acid
   Show/Hide
C24H23F3N2O5
 1
1
EC50 = 2393 nM
   TI
   LI
   LO
   TS
CP0225562
2-{4-[3-(2-phenyl-7-propyl-1H-indol-6-yloxy)propoxy]-indol-1-yl}ethanoic acid
   Show/Hide
C30H30N2O4
 1
1
EC50 = 2820 nM
   TI
   LI
   LO
   TS
CP0215541
2-{4-[2-methyl-3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}ethanoic acid
   Show/Hide
C25H25F3N2O5
 1
1
EC50 = 3030 nM
   TI
   LI
   LO
   TS
CP0408694
2-(1-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propyl)-1H-indol-6-yloxy)acetic acid
   Show/Hide
C33H31NO5
 1
1
EC50 = 3470 nM
   TI
   LI
   LO
   TS
CP0154580
2-(6-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C33H31NO5
 1
1
EC50 = 3870 nM
   TI
   LI
   LO
   TS
CP0278453
2-(6-(3-(4-(4-fluorobenzoyl)-2-propylphenoxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C29H28FNO5
 1
1
EC50 = 4000 nM
   TI
   LI
   LO
   TS
CP0343912
2-{4-[3-(3-phenyl-7-propylbenzo[b]furan-6-yloxy)propoxy]-indol-1-yl}ethanoic acid
   Show/Hide
C30H29NO5
 1
1
EC50 = 4150 nM
   TI
   LI
   LO
   TS
CP0425407
2-(1-(3-(6-benzoyl-1-propylnaphthalen-2-yloxy)propyl)-1H-indol-4-yloxy)acetic acid
   Show/Hide
C33H31NO5
 1
1
EC50 = 4220 nM
   TI
   LI
   LO
   TS
CP0319342
2-ethyl-2-{5-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}ethanoic acid
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C26H27F3N2O5
 1
1
EC50 = 5900 nM
   TI
   LI
   LO
   TS
CP0280352
2-{5-[3-(3-cyano-7-propyl-1H-indol-6-yloxy)propoxy]-indol-1-yl}ethanoic acid
   Show/Hide
C25H25N3O4
 1
1
EC50 = 9170 nM
   TI
   LI
   LO
   TS
CP0160416
2-{4-[3-(2-phenyl-7-propylbenzo[b]furan-6-yloxy)propoxy]-indol-1-yl}ethanoic acid
   Show/Hide
C30H29NO5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0199459
2-{4-[2-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)ethoxy]-1H-indol-1-yl}ethanoic acid
   Show/Hide
C23H21F3N2O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0199460
2-{4-[3-methyl-5-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)pentyloxy]-1H-indol-1-yl}ethanoic acid
   Show/Hide
C27H29F3N2O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0254794
2-ethyl-2-{4-[3-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)propoxy]-1H-indol-1-yl}ethanoic acid
   Show/Hide
C26H27F3N2O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0280353
2-(5-{3-[3-(2,2,2-trifluoroethyl-1-one)-7-propyl-1H-indol-6-yloxy]propoxy}indol-1-yl)ethanoic acid
   Show/Hide
C26H25F3N2O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0319341
2-{4-[5-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)pentyloxy]-1H-indol-1-yl}ethanoic acid
   Show/Hide
C26H27F3N2O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0370166
2-{5-[3-methyl-5-(7-propyl-3-trifluoromethylbenzo[d]isoxazol-6-yloxy)pentyloxy]-1H-indol-1-yl}ethanoic acid
   Show/Hide
C27H29F3N2O5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0099074
2-(4-(3-(4-(4-fluorobenzoyl)phenoxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C26H22FNO5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0099078
2-(4-(3-(6-benzoylnaphthalen-2-yloxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C30H25NO5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0104519
2-(6-(3-(4-(4-fluorobenzoyl)phenoxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C26H22FNO5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0194312
2-(4-(3-(4-(4-fluorobenzoyl)-2-propylphenoxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C29H28FNO5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0194328
2-(6-(3-(6-benzoylnaphthalen-2-yloxy)propoxy)-1H-indol-1-yl)acetic acid
   Show/Hide
C30H25NO5
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS