General Information of the Protein
| Protein ID |
PT04436
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| Protein Name |
UMP-CMP kinase
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| Secondarily Protein Name |
Deoxycytidylate kinase
Nucleoside-diphosphate kinase
Uridine monophosphate/cytidine monophosphate kinase
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| Gene Name |
CMPK1
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| Secondarily Gene Name |
CMK
CMPK
UCK
UMK
UMPK
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| Sequence |
MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG
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| Organism |
Homo sapiens, Human
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| Protein Classification |
Enzyme
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| Function |
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
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| Uniprot ID |
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| Ensembl ID | |||||
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| Subcellular Location |
Nucleus
Cytoplasm
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000148 , Huh-7
