General Information of the Protein
| Protein ID |
PT00295
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| Protein Name |
Capsid protein
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| Secondarily Protein Name |
Core antigen
Core protein
HBcAg
p21.5
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| Gene Name |
HBCAG
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| Secondarily Gene Name |
C
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| Sequence |
MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
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| Organism |
Hepatitis B virus, HBV
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| Protein Classification |
Structural protein
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| Function |
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.
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| Uniprot ID | |||||
| Subcellular Location |
Secreted
Virion
Host cytoplasm
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Map of Molecular Bioactivity Related to the Protein
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Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000148 , Huh-7
Cell Line ID: CL000617 , Hep-G2/2.2.15
Cell Line ID: CL000628 , HepAD38
Cell Line ID: CL000499 , HepDES19
Biochemical Assays
| Compound ID | Compound Name | Compound Formula | |
| CP0274362 |
BAY-414109
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C18H13ClF3N3O2
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1 |
| 1 | IC50 = 430 nM | ||
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