| Compound ID |
Compound Name |
Compound Formula |
|
CP0451286
|
ethyl (4R)-4-(2-bromo-4-fluorophenyl)-6-(morpholin-4-ylmethyl)-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
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|
C21H22BrFN4O3S
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0444738
|
ethyl 4-(2-bromo-4-fluorophenyl)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
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|
C24H26BrFN4O4S
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0069893
|
Epivir
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|
C8H11N3O3S
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0419007
|
ethyl 4-(2-bromo-4-fluorophenyl)-6-[(1,3-dioxo-2,8-diazaspiro[4.5]decan-8-yl)methyl]-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
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|
C25H25BrFN5O4S
|
1
|
| 1 |
EC50 = 680 nM
|
|
|
|
CP0451289
|
ethyl 4-(2-bromo-4-fluorophenyl)-6-[(3-oxo-2,7-diazaspiro[3.5]nonan-7-yl)methyl]-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
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|
C24H25BrFN5O3S
|
1
|
| 1 |
EC50 = 1170 nM
|
|
|
|
CP0423573
|
ethyl 6-[(2-benzyl-1,3-dioxo-2,7-diazaspiro[4.4]nonan-7-yl)methyl]-4-(2-bromo-4-fluorophenyl)-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
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|
C31H29BrFN5O4S
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0419018
|
ethyl 4-(2-bromo-4-fluorophenyl)-6-[(8-oxo-2,7-diazaspiro[4.4]nonan-2-yl)methyl]-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
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|
C24H25BrFN5O3S
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0419011
|
ethyl 4-(2-bromo-4-fluorophenyl)-6-[(1-oxo-2,8-diazaspiro[4.5]decan-8-yl)methyl]-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
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|
C25H27BrFN5O3S
|
1
|
| 1 |
EC50 = 3430 nM
|
|
|
|
CP0451284
|
ethyl 4-(2-bromo-4-fluorophenyl)-6-[(3-oxo-2,8-diazaspiro[4.5]decan-8-yl)methyl]-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidine-5-carboxylate
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|
C25H27BrFN5O3S
|
1
|
| 1 |
EC50 = 3800 nM
|
|
|
|
CP0547766
|
tert-butyl 7-[[4-(2-bromo-4-fluorophenyl)-5-ethoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-2,7-diazaspiro[4.4]nonane-2-carboxylate
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|
C29H35BrFN5O4S
|
1
|
| 1 |
EC50 = 4830 nM
|
|
|
|
CP0451288
|
tert-butyl 2-[[4-(2-bromo-4-fluorophenyl)-5-ethoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-1-oxo-2,7-diazaspiro[4.4]nonane-7-carboxylate
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|
C29H33BrFN5O5S
|
1
|
| 1 |
EC50 = 5170 nM
|
|
|
|
CP0517079
|
tert-butyl 7-[[4-(2-bromo-4-fluorophenyl)-5-ethoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-2,7-diazaspiro[3.4]octane-2-carboxylate
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|
C28H33BrFN5O4S
|
1
|
| 1 |
EC50 = 8830 nM
|
|
|
|
CP0451056
|
tert-butyl 2-[[4-(2-bromo-4-fluorophenyl)-5-ethoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-3-oxo-2,7-diazaspiro[4.4]nonane-7-carboxylate
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|
C29H33BrFN5O5S
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0444739
|
tert-butyl 7-[[4-(2-bromo-4-fluorophenyl)-5-ethoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
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|
C29H35BrFN5O4S
|
1
|
| 1 |
EC50 = 10370 nM
|
|
|
|
CP0520865
|
tert-butyl 6-[[4-(2-bromo-4-fluorophenyl)-5-ethoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-7-oxo-2,6-diazaspiro[3.4]octane-2-carboxylate
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|
C28H31BrFN5O5S
|
1
|
| 1 |
EC50 = 13270 nM
|
|
|
