General Information of the Cell Line
Cell Line ID
CL000704
Cell Line Name
HepG2-Lucia AhR
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_A8BT
Tissue Information
Liver
Disease
Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT02265, Aryl hydrocarbon receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0543877
 Compound Info 
6-bromo-2-(4-bromophenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7Br2N3
  1
1
EC50 = 0.03 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0580167
 Compound Info 
6-bromo-2-(4-bromophenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H7Br2N3O
  1
1
EC50 = 0.27 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579967
 Compound Info 
2-(4-bromophenyl)-6-chloro-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H7BrClN3O
  1
1
EC50 = 0.34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0574489
 Compound Info 
6-bromo-2-[4-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C13H7BrF3N3
  1
1
EC50 = 0.44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576555
 Compound Info 
6-bromo-2-(4-chlorophenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7BrClN3
  1
1
EC50 = 0.83 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569403
 Compound Info 
6-bromo-2-(3-bromophenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7Br2N3
  1
1
EC50 = 9.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579970
 Compound Info 
2-(4-bromophenyl)-[1,2,4]triazolo[1,5-a]pyridine-6-carbonitrile
   Show/Hide
C13H7BrN4
  1
1
EC50 = 23 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577740
 Compound Info 
Benvitimod
   Show/Hide
C17H18O2
  1
1
EC50 = 27.34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577687
 Compound Info 
7-bromo-2-(4-bromophenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H7Br2N3O
  1
1
EC50 = 62 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0574488
 Compound Info 
2-(4-bromophenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium-6-carbonitrile
   Show/Hide
C13H7BrN4O
  1
1
EC50 = 77 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577631
 Compound Info 
2-(4-bromophenyl)-7-fluoro-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H7BrFN3O
  1
1
EC50 = 83 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552049
 Compound Info 
2-(4-bromophenyl)-6-chloro-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7BrClN3
  1
1
EC50 = 156 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569404
 Compound Info 
8-bromo-2-(4-bromophenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7Br2N3
  1
1
EC50 = 172 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579968
 Compound Info 
5-bromo-2-(4-bromophenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H7Br2N3O
  1
1
EC50 = 205 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578915
 Compound Info 
2-(4-bromophenyl)-7-chloro-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H7BrClN3O
  1
1
EC50 = 271 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0580168
 Compound Info 
8-bromo-2-(4-bromophenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H7Br2N3O
  1
1
EC50 = 374 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552048
 Compound Info 
5-bromo-2-(4-bromophenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7Br2N3
  1
1
EC50 = 625 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576557
 Compound Info 
7-bromo-2-(4-bromophenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7Br2N3
  1
1
EC50 = 625 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579969
 Compound Info 
2-(4-bromophenyl)-6-fluoro-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7BrFN3
  1
1
EC50 = 658 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576554
 Compound Info 
2-(4-bromophenyl)-3-oxido-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C13H7BrF3N3O
  1
1
EC50 = 759 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568238
 Compound Info 
2-(4-bromophenyl)-6-methyl-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C13H10BrN3O
  1
1
EC50 = 842 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552047
 Compound Info 
2-(4-bromophenyl)-6-fluoro-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H7BrFN3O
  1
1
EC50 = 1093 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0577561
 Compound Info 
6-bromo-2-(4-fluorophenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7BrFN3
  1
1
EC50 = 1185 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0580169
 Compound Info 
6-bromo-2-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C13H10BrN3
  1
1
EC50 = 1895 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576556
 Compound Info 
6-bromo-2-(2-bromophenyl)-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H7Br2N3
  1
1
EC50 = 2430 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576550
 Compound Info 
2-(4-bromophenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H8BrN3O
  1
1
EC50 = 2500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578914
 Compound Info 
2-(4-chlorophenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H8ClN3O
  1
1
EC50 = 3330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0552046
 Compound Info 
3-oxido-2-pyridin-4-yl-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C11H8N4O
  1
1
EC50 = 4660 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0568239
 Compound Info 
2-(4-bromophenyl)-6-methyl-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C13H10BrN3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0569402
 Compound Info 
2-naphthalen-2-yl-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C16H11N3O
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570191
 Compound Info 
2-(4-methoxyphenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C13H11N3O2
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0571261
 Compound Info 
6-bromo-2-phenyl-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C12H8BrN3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576551
 Compound Info 
methyl 4-(3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium-2-yl)benzoate
   Show/Hide
C14H11N3O3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0576553
 Compound Info 
2-[5-(4-chlorophenyl)furan-2-yl]-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C16H10ClN3O2
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578360
 Compound Info 
2-(4-fluorophenyl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C12H8FN3O
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578361
 Compound Info 
3-oxido-2-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C11H8N4O
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0578905
 Compound Info 
2-(4-bromophenyl)-[1,2,4]triazolo[1,5-b]isoquinoline
   Show/Hide
C16H10BrN3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579770
 Compound Info 
2-(6-bromopyridin-3-yl)-3-oxido-[1,2,4]triazolo[1,5-a]pyridin-3-ium
   Show/Hide
C11H7BrN4O
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0579771
 Compound Info 
2-(4-bromophenyl)-6-phenyl-[1,2,4]triazolo[1,5-a]pyridine
   Show/Hide
C18H12BrN3
  1
1
EC50 > 10000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Liver)
Cell Line Name Organism Disease
Huh-7
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
HLF
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-7-Lunet
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-7.5
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-5-2
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
PLC/PRF/5
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Hep 3B2.1-7
 Cell Line Info 
Homo sapiens (Human) Childhood hepatocellular carcinoma
VACO 241
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
LM
 Cell Line Info 
Homo sapiens (Human) Extrarenal rhabdoid tumor of the liver
GTL-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
MKN45
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
NCI-N87
 Cell Line Info 
Homo sapiens (Human) Gastric tubular adenocarcinoma
Hep-G2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2/C3A
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
CellSensor ARE-bla Hep G2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2 VA-13
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepDES19
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
DPX2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2/2.2.15
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepAD38
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepG2-hNTCP
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HCCC-9810
 Cell Line Info 
Homo sapiens (Human) Intrahepatic cholangiocarcinoma
SU.86.86
 Cell Line Info 
Homo sapiens (Human) Pancreatic adenocarcinoma
Capan-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
Hepa-1c1c7
 Cell Line Info 
Mus musculus (Mouse) Hepatocellular carcinoma of the mouse
H5
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H4-II-E
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H4-II-E-C3
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
McA-RH7777
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H2.35
 Cell Line Info 
Mus musculus (Mouse) -