General Information of the Cell Line
Cell Line ID
CL000540
Cell Line Name
Huh-5-2
Synonyms
Huh 5-2
5-2
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_X943
Tissue Information
Liver
Disease
Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00013, RNA-directed RNA polymerase
 Protein Info 
Compound ID Compound Name Compound Formula
CP0159312
 Compound Info 
1-Cyclohexyl-2-[2-fluoro-4-(phenyl-pyridin-3-yl-methoxy)-phenyl]-1H-benzoimidazole-5-carboxylic acid
   Show/Hide
C32H28FN3O3
  1
1
EC50 = 1100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099028
 Compound Info 
2-{4-[Bis-(4-dimethylcarbamoyl-phenyl)-methoxy]-2-fluoro-phenyl}-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid
   Show/Hide
C39H39FN4O5
  1
1
EC50 = 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099023
 Compound Info 
2-(4-(bis(4-fluorophenyl)methoxy)-2-fluorophenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
C33H27F3N2O3
  1
1
EC50 = 1600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099024
 Compound Info 
2-(4-(benzhydryloxy)-2-fluorophenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
C33H29FN2O3
  1
1
EC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0153398
 Compound Info 
2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
C33H28F2N2O3
  1
1
EC50 = 2200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099026
 Compound Info 
2-(4-(benzhydryloxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
C33H30N2O3
  1
1
EC50 = 2600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0153397
 Compound Info 
1-Cyclohexyl-2-[4-(di-pyridin-3-yl-methoxy)-2-fluoro-phenyl]-1H-benzoimidazole-5-carboxylic acid
   Show/Hide
C31H27FN4O3
  1
1
EC50 = 2600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099025
 Compound Info 
2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
C33H28F2N2O3
  1
1
EC50 = 2800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0159318
 Compound Info 
2-(4-(bis(4-chlorophenyl)methoxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
C33H28Cl2N2O3
  1
1
EC50 = 3600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0263183
 Compound Info 
1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
C35H34N2O3
  1
1
EC50 = 3700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0099023
 Compound Info 
2-(4-(bis(4-fluorophenyl)methoxy)-2-fluorophenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
 C33H27F3N2O3  1
1
CC50 = 27200 nM
   TI
   LI
   LO
   TS
CP0099024
 Compound Info 
2-(4-(benzhydryloxy)-2-fluorophenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
 C33H29FN2O3  1
1
CC50 = 27300 nM
   TI
   LI
   LO
   TS
CP0099026
 Compound Info 
2-(4-(benzhydryloxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
 C33H30N2O3  1
1
CC50 = 31900 nM
   TI
   LI
   LO
   TS
CP0099028
 Compound Info 
2-{4-[Bis-(4-dimethylcarbamoyl-phenyl)-methoxy]-2-fluoro-phenyl}-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid
   Show/Hide
 C39H39FN4O5  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0153397
 Compound Info 
1-Cyclohexyl-2-[4-(di-pyridin-3-yl-methoxy)-2-fluoro-phenyl]-1H-benzoimidazole-5-carboxylic acid
   Show/Hide
 C31H27FN4O3  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0159312
 Compound Info 
1-Cyclohexyl-2-[2-fluoro-4-(phenyl-pyridin-3-yl-methoxy)-phenyl]-1H-benzoimidazole-5-carboxylic acid
   Show/Hide
 C32H28FN3O3  1
1
CC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0263183
 Compound Info 
1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-benzo[d]imidazole-5-carboxylic acid
   Show/Hide
 C35H34N2O3  1
1
CC50 = 23500 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Liver)
Cell Line Name Organism Disease
Huh-7
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
HLF
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-7-Lunet
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-7.5
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
PLC/PRF/5
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Hep 3B2.1-7
 Cell Line Info 
Homo sapiens (Human) Childhood hepatocellular carcinoma
VACO 241
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
LM
 Cell Line Info 
Homo sapiens (Human) Extrarenal rhabdoid tumor of the liver
GTL-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
MKN45
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
NCI-N87
 Cell Line Info 
Homo sapiens (Human) Gastric tubular adenocarcinoma
Hep-G2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2/C3A
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
CellSensor ARE-bla Hep G2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2 VA-13
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepDES19
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
DPX2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2/2.2.15
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepAD38
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepG2-Lucia AhR
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepG2-hNTCP
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HCCC-9810
 Cell Line Info 
Homo sapiens (Human) Intrahepatic cholangiocarcinoma
SU.86.86
 Cell Line Info 
Homo sapiens (Human) Pancreatic adenocarcinoma
Capan-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
Hepa-1c1c7
 Cell Line Info 
Mus musculus (Mouse) Hepatocellular carcinoma of the mouse
H5
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H4-II-E
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H4-II-E-C3
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
McA-RH7777
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H2.35
 Cell Line Info 
Mus musculus (Mouse) -