Brief Information of the Compound and Protein
Compound Name
2-{4-[Bis-(4-dimethylcarbamoyl-phenyl)-methoxy]-2-fluoro-phenyl}-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid
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PubChem ID
CID: 15956784
Canonical SMILES
CN(C)C(=O)c1ccc(cc1)C(Oc1ccc(-c2nc3cc(ccc3n2C2CCCCC2)C(O)=O)c(F)c1)c1ccc(cc1)C(=O)N(C)C
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Compound Formula C39H39FN4O5
Compound Structure
Protein Name
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000540 Huh-5-2 Homo sapiens (Human)  1
1
EC50 = 1200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 640 nM
2 IC50 = 950 nM