| Compound ID |
Compound Name |
Compound Formula |
|
CP0339286
|
US9265773, 2
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|
C32H24F2N4O5S
|
8
|
| 1 |
EC50 = 1 nM
|
|
| 2 |
EC50 = 1.2 nM
|
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| 3 |
EC50 = 1.6 nM
|
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| 4 |
EC50 = 1.8 nM
|
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| 5 |
EC50 = 2.2 nM
|
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| 6 |
EC50 = 2.3 nM
|
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| 7 |
EC50 = 3.9 nM
|
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| 8 |
EC50 = 7.3 nM
|
|
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CP0031380
|
CHEBI:85083
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|
C22H29FN3O9P
|
2
|
| 1 |
EC50 = 64.26 nM
|
|
| 2 |
EC50 = 102 nM
|
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CP0059885
|
2-(3-(3-(2-chlorobenzyl)ureido)thiophen-2-yl)-5,6-dihydroxypyrimidine-4-carboxylic acid
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|
C17H13ClN4O5S
|
7
|
| 1 |
EC50 = 9300 nM
|
|
| 2 |
IC50 = 36 nM
|
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| 3 |
IC50 = 44 nM
|
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| 4 |
IC50 = 45 nM
|
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| 5 |
IC50 = 48 nM
|
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| 6 |
IC50 = 130 nM
|
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| 7 |
IC50 = 150 nM
|
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CP0034787
|
1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BENZOTHIADIAZIN-3-YL)-6-FLUORO-4-HYDROXYQUINOLIN-2(1H)-ONE
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|
C21H18FN3O4S
|
3
|
| 1 |
IC50 = 10 nM
|
|
| 2 |
IC50 = 13 nM
|
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| 3 |
IC50 = 49 nM
|
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CP0250399
|
1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]-thiadiazin-3-yl)-4-hydroxy-1H-quinolin-2-one
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|
C21H19N3O4S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
CP0334938
|
3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-6-fluoro-4-hydroxy-1-(3-methyl-butyl)-1H-quinolin-2-one
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|
C21H20FN3O4S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
CP0324029
|
2-[[3-(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxoquinolin-6-yl]amino]acetic acid
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|
C23H24N4O6S
|
1
|
| 1 |
IC50 = 21 nM
|
|
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CP0334937
|
4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-6-yloxy]acetamide
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|
C23H24N4O6S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
CP0250390
|
3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-1-furan-3-ylmethyl-4-hydroxy-1H-quinolin-2-one
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|
C21H15N3O5S
|
1
|
| 1 |
IC50 = 27 nM
|
|
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CP0040918
|
3-(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2-one
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|
C21H21N3O4S
|
2
|
| 1 |
IC50 = 32 nM
|
|
| 2 |
IC50 = 200 nM
|
|
|
CP0255446
|
6-Amino-1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-
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|
C21H20N4O4S
|
1
|
| 1 |
IC50 = 32 nM
|
|
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CP0255450
|
4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-6-yloxy]acetonitrile
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|
C23H22N4O5S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
CP0367897
|
2-[4-(4'-Chloro-4-methoxy-biphenyl-2-ylmethoxy)-phenyl]-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid
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|
C34H31ClN2O4
|
1
|
| 1 |
IC50 = 37 nM
|
|
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CP0255455
|
6-chloro-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-1H-quinolin-2-one
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|
C21H20ClN3O4S
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
CP0299364
|
3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-6-methyl-1-(3-methylbutyl)-1H-quinolin-2-one
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|
C22H23N3O4S
|
1
|
| 1 |
IC50 = 47 nM
|
|
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CP0250386
|
1-(3,3-dimethylbutyl)-3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-6-(2-hydroxyethylamino)-1H-quinolin-2-one
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|
C24H28N4O5S
|
1
|
| 1 |
IC50 = 48 nM
|
|
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CP0099391
|
1-cyclobutylmethyl-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-1H-quinolin-2-one
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|
C21H19N3O4S
|
1
|
| 1 |
IC50 = 49 nM
|
|
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CP0190530
|
((R)-5-cyano-6-fluoro-8-methyl-1-propyl-3,4-dihydro-1H-benzo[4,5]thieno[2,3-c]pyran-1-yl)-acetic acid
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|
C18H18FNO3S
|
1
|
| 1 |
IC50 = 50 nM
|
|
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CP0255452
|
6-amino-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-1H-quinolin-2-one
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|
C21H22N4O4S
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
CP0360943
|
(S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyrrolidine-2-carboxylic acid
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|
C11H10Cl3NO5S
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
CP0099024
|
2-(4-(benzhydryloxy)-2-fluorophenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
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|
C33H29FN2O3
|
2
|
| 1 |
IC50 = 96 nM
|
|
| 2 |
IC50 = 800 nM
|
|
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CP0083396
|
1-Butyl-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1H-quinolin-2-one
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|
C20H19N3O4S
|
2
|
| 1 |
IC50 = 100 nM
|
|
| 2 |
IC50 = 200 nM
|
|
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CP0223342
|
ethyl 2-[[3-(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxoquinolin-6-yl]amino]acetate
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|
C25H28N4O6S
|
1
|
| 1 |
IC50 = 115 nM
|
|
|
CP0159312
|
1-Cyclohexyl-2-[2-fluoro-4-(phenyl-pyridin-3-yl-methoxy)-phenyl]-1H-benzoimidazole-5-carboxylic acid
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|
C32H28FN3O3
|
2
|
| 1 |
IC50 = 270 nM
|
|
| 2 |
IC50 = 800 nM
|
|
|
CP0099023
|
2-(4-(bis(4-fluorophenyl)methoxy)-2-fluorophenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
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|
C33H27F3N2O3
|
2
|
| 1 |
IC50 = 300 nM
|
|
| 2 |
IC50 = 840 nM
|
|
|
CP0334939
|
3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-5-fluoro-4-hydroxy-1-(3-methylbutyl)-1H-quinolin-2-one
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|
C21H20FN3O4S
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
CP0185596
|
5,8-dichloro-3-propyl-1,2,3,4-tetrahydrocyclopenta[b]indole-3-carboxylic acid
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|
C15H15Cl2NO2
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
CP0099026
|
2-(4-(benzhydryloxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
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|
C33H30N2O3
|
2
|
| 1 |
IC50 = 590 nM
|
|
| 2 |
IC50 = 1300 nM
|
|
|
CP0099028
|
2-{4-[Bis-(4-dimethylcarbamoyl-phenyl)-methoxy]-2-fluoro-phenyl}-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid
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|
C39H39FN4O5
|
2
|
| 1 |
IC50 = 640 nM
|
|
| 2 |
IC50 = 950 nM
|
|
|
CP0099025
|
2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
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|
C33H28F2N2O3
|
2
|
| 1 |
IC50 = 760 nM
|
|
| 2 |
IC50 = 1900 nM
|
|
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CP0153398
|
2-(4-(bis(4-fluorophenyl)methoxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
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|
C33H28F2N2O3
|
2
|
| 1 |
IC50 = 800 nM
|
|
| 2 |
IC50 = 1700 nM
|
|
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CP0159318
|
2-(4-(bis(4-chlorophenyl)methoxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid
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|
C33H28Cl2N2O3
|
2
|
| 1 |
IC50 = 930 nM
|
|
| 2 |
IC50 = 2400 nM
|
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CP0153397
|
1-Cyclohexyl-2-[4-(di-pyridin-3-yl-methoxy)-2-fluoro-phenyl]-1H-benzoimidazole-5-carboxylic acid
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|
C31H27FN4O3
|
2
|
| 1 |
IC50 = 1100 nM
|
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| 2 |
IC50 = 2200 nM
|
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CP0263183
|
1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-benzo[d]imidazole-5-carboxylic acid
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|
C35H34N2O3
|
2
|
| 1 |
IC50 = 1200 nM
|
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| 2 |
IC50 = 3100 nM
|
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CP0645196
|
3-(2-(1-(2-(5-bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-carboxamido)cyclobutyl)-1-methyl-1H-benzo[d]imidazol-6-yl)acrylic acid
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|
C34H33BrN6O3
|
1
|
| 1 |
IC50 ~ 19 nM
|
|
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CP0255468
|
3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-phenyl-1Hquinolin-2-one
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|
C22H15N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
