General Information of the Cell Line
Cell Line ID
CL000240
Cell Line Name
CellSensor ARE-bla Hep G2
Synonyms
ARE-bla Hep G2
ARE-bla HepG2
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_KS12
Tissue Information
Liver
Disease
Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT04367, Nuclear factor erythroid 2-related factor 2
 Protein Info 
Compound ID Compound Name Compound Formula
CP0055024
 Compound Info 
4-(Methylsulfinyl)Butyl Isothiocyanate
   Show/Hide
C6H11NOS2
  1
1
EC50 = 19080 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0374967
 Compound Info 
(3Z)-9,10-dimethoxy-3-[2-(3-nitrophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C22H21N3O6
  1
1
EC50 = 49610 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0395550
 Compound Info 
(3Z)-8-methoxy-3-phenacylidene-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H20N2O3
  1
1
EC50 = 58540 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0414769
 Compound Info 
(3Z)-3-[2-(3,5-difluorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H16F2N2O2
  1
1
EC50 = 58860 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0414768
 Compound Info 
(3Z)-3-[2-(3-bromophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17BrN2O2
  1
1
EC50 = 59120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0394955
 Compound Info 
(3Z)-3-[2-(2-fluorophenyl)-2-oxoethylidene]-9,10-dimethoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C22H21FN2O4
  1
1
EC50 = 75850 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388049
 Compound Info 
(3Z)-3-[2-(4-fluorophenyl)-2-oxoethylidene]-9,10-dimethoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C22H21FN2O4
  1
1
EC50 = 81540 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0374926
 Compound Info 
(3Z)-3-[2-(4-fluorophenyl)-2-oxoethylidene]-10-methoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19FN2O3
  1
1
EC50 = 87950 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0010068
 Compound Info 
CHEBI:78886
   Show/Hide
C10H14O2
  1
1
EC50 = 91530 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0395555
 Compound Info 
(3Z)-3-[2-(3-fluorophenyl)-2-oxoethylidene]-9,10-dimethoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C22H21FN2O4
  1
1
EC50 = 92000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0410518
 Compound Info 
(3Z)-3-[2-(3,4-dimethoxyphenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C22H22N2O4
  1
1
EC50 = 93020 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0374964
 Compound Info 
(3Z)-3-[2-(4-methylphenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H20N2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0374968
 Compound Info 
(3Z)-3-[2-(2-methoxyphenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H20N2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385585
 Compound Info 
(3Z)-3-phenacylidene-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H18N2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385586
 Compound Info 
(3Z)-3-[2-(4-chlorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17ClN2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385608
 Compound Info 
(3Z)-3-[2-(4-nitrophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17N3O4
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385609
 Compound Info 
(3Z)-10-methoxy-3-[2-(3-methoxyphenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C22H22N2O4
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385610
 Compound Info 
(3Z)-10-methoxy-3-[2-(3-nitrophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19N3O5
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0385611
 Compound Info 
(3Z)-3-[2-(3-chlorophenyl)-2-oxoethylidene]-10-methoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19ClN2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388043
 Compound Info 
(3Z)-3-[2-oxo-2-[3-(trifluoromethyl)phenyl]ethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H17F3N2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388046
 Compound Info 
(3Z)-3-[2-(2-fluorophenyl)-2-oxoethylidene]-8-methoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19FN2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388047
 Compound Info 
(3Z)-3-[2-(3-fluorophenyl)-2-oxoethylidene]-8-methoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19FN2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388050
 Compound Info 
(3Z)-3-[2-(2-nitrophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17N3O4
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0388058
 Compound Info 
(3Z)-3-[2-(2,4-dichlorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H16Cl2N2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0394953
 Compound Info 
(3Z)-10-methoxy-3-phenacylidene-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H20N2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0394954
 Compound Info 
(3Z)-9,10-dimethoxy-3-[2-(3-methoxyphenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C23H24N2O5
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0394956
 Compound Info 
(3Z)-3-[2-(3-chlorophenyl)-2-oxoethylidene]-9,10-dimethoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C22H21ClN2O4
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0394958
 Compound Info 
(3Z)-3-[2-(3-fluorophenyl)-2-oxoethylidene]-9-methoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19FN2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0395552
 Compound Info 
(3Z)-3-[2-(3-nitrophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17N3O4
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0395553
 Compound Info 
(3Z)-3-[2-(2-fluorophenyl)-2-oxoethylidene]-10-methoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19FN2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0395554
 Compound Info 
(3Z)-3-[2-(2-fluorophenyl)-2-oxoethylidene]-9-methoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19FN2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0395556
 Compound Info 
(3Z)-3-[2-(3-fluorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17FN2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0395557
 Compound Info 
(3Z)-3-[2-(4-fluorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17FN2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0403895
 Compound Info 
(3Z)-9-methoxy-3-phenacylidene-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H20N2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0403896
 Compound Info 
(3Z)-9,10-dimethoxy-3-phenacylidene-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C22H22N2O4
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0403897
 Compound Info 
(3Z)-3-[2-(3-fluorophenyl)-2-oxoethylidene]-10-methoxy-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H19FN2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0403898
 Compound Info 
(3Z)-3-[2-(4-methoxyphenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H20N2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0405918
 Compound Info 
(3Z)-3-[2-(3,4-difluorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H16F2N2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0410467
 Compound Info 
(3Z)-3-[2-(2-chlorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17ClN2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0414771
 Compound Info 
(3Z)-3-[2-(2-fluorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17FN2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0414775
 Compound Info 
(3Z)-3-[2-oxo-2-(4-phenylphenyl)ethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C26H22N2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0426757
 Compound Info 
(3Z)-3-[2-(3-methoxyphenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C21H20N2O3
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0459316
 Compound Info 
(3Z)-3-[2-(3-chlorophenyl)-2-oxoethylidene]-2,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
   Show/Hide
C20H17ClN2O2
  1
1
EC50 > 100000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Liver)
Cell Line Name Organism Disease
Huh-7
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
HLF
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-7-Lunet
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-7.5
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Huh-5-2
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
PLC/PRF/5
 Cell Line Info 
Homo sapiens (Human) Adult hepatocellular carcinoma
Hep 3B2.1-7
 Cell Line Info 
Homo sapiens (Human) Childhood hepatocellular carcinoma
VACO 241
 Cell Line Info 
Homo sapiens (Human) Colon carcinoma
LM
 Cell Line Info 
Homo sapiens (Human) Extrarenal rhabdoid tumor of the liver
GTL-16
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
MKN45
 Cell Line Info 
Homo sapiens (Human) Gastric adenocarcinoma
NCI-N87
 Cell Line Info 
Homo sapiens (Human) Gastric tubular adenocarcinoma
Hep-G2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2/C3A
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2 VA-13
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepDES19
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
DPX2
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
Hep-G2/2.2.15
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepAD38
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepG2-Lucia AhR
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HepG2-hNTCP
 Cell Line Info 
Homo sapiens (Human) Hepatoblastoma
HCCC-9810
 Cell Line Info 
Homo sapiens (Human) Intrahepatic cholangiocarcinoma
SU.86.86
 Cell Line Info 
Homo sapiens (Human) Pancreatic adenocarcinoma
Capan-1
 Cell Line Info 
Homo sapiens (Human) Pancreatic ductal adenocarcinoma
Hepa-1c1c7
 Cell Line Info 
Mus musculus (Mouse) Hepatocellular carcinoma of the mouse
H5
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H4-II-E
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H4-II-E-C3
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
McA-RH7777
 Cell Line Info 
Rattus norvegicus (Rat) Rat hepatocellular carcinoma
H2.35
 Cell Line Info 
Mus musculus (Mouse) -