Compound ID |
Compound Name |
Compound Formula |
CP0394759
|
2-[4-({[3-(3-benzyl-8-chloroquinolin-4-yl)phenyl]amino}methyl)phenyl]acetic acid
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|
C31H25ClN2O2
|
1
|
1 |
EC50 = 54 nM
|
|
|
CP0274549
|
3-ethyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
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|
C25H20F3NO2S
|
1
|
1 |
EC50 = 76 nM
|
|
|
CP0221684
|
2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid
Show/Hide
|
C32H25F3N2O2
|
2
|
1 |
EC50 = 87 nM
|
|
|
2 |
EC50 = 90 nM
|
|
|
CP0203734
|
2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid
Show/Hide
|
C32H24F3NO3
|
2
|
1 |
EC50 = 90 nM
|
|
|
2 |
EC50 = 93 nM
|
|
|
CP0158348
|
3-isopropyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C26H22F3NO2S
|
1
|
1 |
EC50 = 91 nM
|
|
|
CP0372436
|
biarylether amide quinoline, 4e
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|
C34H27F3N2O2
|
1
|
1 |
EC50 = 98 nM
|
|
|
CP0224486
|
3-benzyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C30H22F3NO2S
|
1
|
1 |
EC50 = 100 nM
|
|
|
CP0308201
|
4-(3'-(methylsulfonyl)biphenyl-3-yl)-3-propyl-8-(trifluoromethyl)quinoline
Show/Hide
|
C26H22F3NO2S
|
1
|
1 |
EC50 = 106 nM
|
|
|
CP0003740
|
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
Show/Hide
|
C17H12F9NO3S
|
3
|
1 |
EC50 = 135 nM
|
|
|
2 |
EC50 = 170 nM
|
|
|
3 |
EC50 = 178 nM
|
|
|
CP0402007
|
biarylether amide quinoline, 4g
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|
C34H27F3N2O3
|
1
|
1 |
EC50 = 138 nM
|
|
|
CP0402006
|
biarylether amide quinoline, 4d
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|
C34H29F3N2O2
|
1
|
1 |
EC50 = 144 nM
|
|
|
CP0234158
|
2-benzyl-3-[3-(3-methylsulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C28H21F3N2O3S
|
1
|
1 |
EC50 = 144 nM
|
|
|
CP0107209
|
4-(4'-fluoro-3'-(methylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline
Show/Hide
|
C24H17F4NO2S
|
1
|
1 |
EC50 = 161 nM
|
|
|
CP0372461
|
biarylether amide quinoline, 4f
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|
C35H29F3N2O2
|
1
|
1 |
EC50 = 170 nM
|
|
|
CP0239960
|
3-[[3-[3-(3-methylsulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]methyl]-1,3-thiazolidine
Show/Hide
|
C25H22F3N3O3S2
|
1
|
1 |
EC50 = 170 nM
|
|
|
CP0290643
|
3-methyl-4-(4'-methyl-3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C25H20F3NO2S
|
1
|
1 |
EC50 = 175 nM
|
|
|
CP0128474
|
3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline
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|
C24H18F3NO3S
|
1
|
1 |
EC50 = 183 nM
|
|
|
CP0308202
|
4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline
Show/Hide
|
C24H16F5NO2S
|
1
|
1 |
EC50 = 195 nM
|
|
|
CP0431991
|
2-[4-({[3-(3-benzyl-8-methylquinolin-4-yl)phenyl]amino}methyl)phenyl]acetic acid
Show/Hide
|
C32H28N2O2
|
1
|
1 |
EC50 = 267 nM
|
|
|
CP0294748
|
3-methyl-4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C24H18F3NO2S
|
1
|
1 |
EC50 = 284 nM
|
|
|
CP0006936
|
2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid
Show/Hide
|
C33H31ClF3NO3
|
1
|
1 |
EC50 = 310 nM
|
|
|
CP0287908
|
2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)naphthalen-1-yl)acetic acid
Show/Hide
|
C36H27F3N2O2
|
1
|
1 |
EC50 = 355 nM
|
|
|
CP0038715
|
4-(4'-fluoro-3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C23H15F4NO2S
|
1
|
1 |
EC50 = 512 nM
|
|
|
CP0158347
|
4-(3'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C23H16F3NO2S
|
1
|
1 |
EC50 = 525 nM
|
|
|
CP0107210
|
4-(2',4'-difluoro-5'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C23H14F5NO2S
|
1
|
1 |
EC50 = 565 nM
|
|
|
CP0439795
|
biarylether amide quinoline, 4p
Show/Hide
|
C27H23ClN2O3
|
1
|
1 |
EC50 = 572 nM
|
|
|
CP0107208
|
4-(3'-(ethylsulfonyl)biphenyl-3-yl)-3-methyl-8-(trifluoromethyl)quinoline
Show/Hide
|
C25H20F3NO2S
|
1
|
1 |
EC50 = 580 nM
|
|
|
CP0345734
|
2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid
Show/Hide
|
C29H21F3N2O2
|
1
|
1 |
EC50 = 622 nM
|
|
|
CP0095700
|
2-methyl-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole
Show/Hide
|
C22H17F3N2O3S
|
1
|
1 |
EC50 = 640 nM
|
|
|
CP0353476
|
biarylether amide quinoline, 4i
Show/Hide
|
C24H19ClN2O2
|
1
|
1 |
EC50 = 800 nM
|
|
|
CP0096814
|
5-Chloro-3-methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]quinoxaline
Show/Hide
|
C22H17ClN2O2S
|
1
|
1 |
EC50 = 860 nM
|
|
|
CP0234122
|
3-[3-(3-methylsulfonylphenoxy)phenyl]-2-(piperidin-1-ylmethyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C27H26F3N3O3S
|
1
|
1 |
EC50 = 920 nM
|
|
|
CP0268795
|
3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)-N-(4-methoxybenzyl)-N-methylbenzenesulfonamide
Show/Hide
|
C31H30ClN3O4S
|
1
|
1 |
EC50 = 930 nM
|
|
|
CP0422781
|
2-[(2,4-dimethylphenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
Show/Hide
|
C23H18F4N2
|
1
|
1 |
EC50 = 990 nM
|
|
|
CP0115565
|
4-(3'-(ethylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C24H18F3NO2S
|
1
|
1 |
EC50 = 1080 nM
|
|
|
CP0268792
|
3-[3-(3-methylsulfonylphenoxy)phenyl]-2-phenyl-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C27H19F3N2O3S
|
1
|
1 |
EC50 = 1110 nM
|
|
|
CP0389693
|
3-Benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]-phenyl}-8-(trifluoromethyl)cinnoline
Show/Hide
|
C32H24F3N3O
|
1
|
1 |
EC50 = 1160 nM
|
|
|
CP0493912
|
biarylether amide quinoline, 4k
Show/Hide
|
C26H23ClN2O2
|
1
|
1 |
EC50 = 1180 nM
|
|
|
CP0226706
|
2-ethyl-3-[3-(3-methylsulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C23H19F3N2O3S
|
1
|
1 |
EC50 = 1220 nM
|
|
|
CP0491797
|
biarylether amide quinoline, 4j
Show/Hide
|
C25H21ClN2O2
|
1
|
1 |
EC50 = 1272 nM
|
|
|
CP0439790
|
biarylether amide quinoline, 4b
Show/Hide
|
C33H27F3N2O2
|
1
|
1 |
EC50 = 1525 nM
|
|
|
CP0144261
|
3-(3-(8-chloro-2-isopropylimidazo[1,2-a]pyridin-3-yl)phenoxy)-N-methylbenzenesulfonamide
Show/Hide
|
C23H22ClN3O3S
|
1
|
1 |
EC50 = 1610 nM
|
|
|
CP0144282
|
8-chloro-2-isopropyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)imidazo[1,2-a]pyridine
Show/Hide
|
C23H21ClN2O3S
|
1
|
1 |
EC50 = 1660 nM
|
|
|
CP0144260
|
2-imidazol-1-yl-3-[3-(3-methylsulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C24H17F3N4O3S
|
1
|
1 |
EC50 = 1700 nM
|
|
|
CP0128007
|
4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide
Show/Hide
|
C24H16ClF3N2O4S
|
1
|
1 |
EC50 = 1700 nM
|
|
|
CP0255636
|
3-[3-(3-methylsulfonylphenoxy)phenyl]-2-propan-2-yl-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C24H21F3N2O3S
|
1
|
1 |
EC50 = 1860 nM
|
|
|
CP0240192
|
3-Ethyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline
Show/Hide
|
C24H19F3N2O2S
|
1
|
1 |
EC50 = 2020 nM
|
|
|
CP0268793
|
2-tert-butyl-3-[3-(3-methylsulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C25H23F3N2O3S
|
1
|
1 |
EC50 = 2180 nM
|
|
|
CP0144257
|
3-(3-(3-(ethylsulfonyl)phenoxy)phenyl)-2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C23H19F3N2O3S
|
1
|
1 |
EC50 = 2280 nM
|
|
|
CP0191445
|
2-methyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C22H17F3N2O3S
|
1
|
1 |
EC50 = 2540 nM
|
|
|
CP0372500
|
3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][(1-methyl-1H-indol-2-yl)methyl]amine
Show/Hide
|
C31H25ClN4
|
1
|
1 |
EC50 = 2780 nM
|
|
|
CP0422782
|
2-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
Show/Hide
|
C21H13ClF4N2
|
1
|
1 |
EC50 = 2890 nM
|
|
|
CP0166339
|
2-ethyl-3-(3-(3-(methylsulfonyl)benzyl)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C24H21F3N2O2S
|
1
|
1 |
EC50 = 3200 nM
|
|
|
CP0453672
|
2-benzyl-3-aryl-7-trifluoromethylindazole, 5
Show/Hide
|
C21H15F3N2
|
1
|
1 |
EC50 = 3260 nM
|
|
|
CP0224483
|
3-benzyl-4-(4'-(methylsulfonyl)biphenyl-3-yl)-8-(trifluoromethyl)quinoline
Show/Hide
|
C30H22F3NO2S
|
1
|
1 |
EC50 = 3300 nM
|
|
|
CP0389691
|
3-(3-benzyl-8-chlorocinnolin-4-yl)-N-[[2-chloro-3-(trifluoromethyl)phenyl]methyl]aniline
Show/Hide
|
C29H20Cl2F3N3
|
1
|
1 |
EC50 = 3630 nM
|
|
|
CP0418129
|
3-Benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline
Show/Hide
|
C30H19F7N2O
|
1
|
1 |
EC50 = 3650 nM
|
|
|
CP0013590
|
2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
Show/Hide
|
C21H12ClF5N2
|
1
|
1 |
EC50 = 3670 nM
|
|
|
CP0271955
|
2-isopropyl-3-(3-(3-(methylsulfonyl)phenoxy)phenyl)imidazo[1,2-a]pyridine-8-carbonitrile
Show/Hide
|
C24H21N3O3S
|
1
|
1 |
EC50 = 3900 nM
|
|
|
CP0144311
|
3-(3-(3-(isopropylsulfonyl)phenoxy)phenyl)-2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C24H21F3N2O3S
|
1
|
1 |
EC50 = 4100 nM
|
|
|
CP0039716
|
3-(4-fluorophenyl)-2-[(2-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole
Show/Hide
|
C21H13F5N2
|
1
|
1 |
EC50 = 4150 nM
|
|
|
CP0256824
|
2-(5-((3-(3-methyl-8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid
Show/Hide
|
C30H23F3N2O2
|
1
|
1 |
EC50 = 4167 nM
|
|
|
CP0400998
|
3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-N-[(1-methylindol-7-yl)methyl]aniline
Show/Hide
|
C33H26F3N3
|
1
|
1 |
EC50 = 4170 nM
|
|
|
CP0481385
|
2-benzyl-3-aryl-7-trifluoromethylindazole, 15
Show/Hide
|
C21H13F5N2
|
1
|
1 |
EC50 = 5720 nM
|
|
|
CP0144258
|
3-(3-(3-(2-methyl-8-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl)phenoxy)phenylsulfonyl)propan-1-ol
Show/Hide
|
C24H21F3N2O4S
|
1
|
1 |
EC50 = 6000 nM
|
|
|
CP0144283
|
2-isopropyl-3-(3-(3-(methylsulfonyl)benzyloxy)phenyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Show/Hide
|
C25H23F3N2O3S
|
1
|
1 |
EC50 = 6500 nM
|
|
|
CP0454258
|
3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)-benzyl]oxy}phenyl)cinnoline
Show/Hide
|
C29H19Cl2F3N2O
|
1
|
1 |
EC50 = 6540 nM
|
|
|
CP0453670
|
2-benzyl-3-aryl-7-trifluoromethylindazole, 20
Show/Hide
|
C21H13ClF4N2
|
1
|
1 |
EC50 = 7440 nM
|
|
|
CP0427245
|
3-Benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline
Show/Hide
|
C30H19ClF6N2O
|
1
|
1 |
EC50 = 8600 nM
|
|
|
CP0434980
|
2-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
Show/Hide
|
C21H13ClF4N2
|
1
|
1 |
EC50 = 9050 nM
|
|
|
CP0422784
|
2-[(4-chloro-2-fluorophenyl)methyl]-3-(4-chlorophenyl)-7-(trifluoromethyl)-2H-indazole
Show/Hide
|
C21H12Cl2F4N2
|
1
|
1 |
EC50 = 9800 nM
|
|
|
CP0389692
|
3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]-N-[(1-methylindol-2-yl)methyl]aniline
Show/Hide
|
C33H26F3N3
|
1
|
1 |
EC50 = 10180 nM
|
|
|
CP0422783
|
2-benzyl-3-aryl-7-trifluoromethylindazole, 19
Show/Hide
|
C21H13Cl2F3N2
|
1
|
1 |
EC50 = 10200 nM
|
|
|
CP0434723
|
2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-chlorophenyl)-7-(trifluoromethyl)-2H-indazole
Show/Hide
|
C21H12Cl2F4N2
|
1
|
1 |
EC50 = 11220 nM
|
|
|
CP0415202
|
2-benzyl-3-aryl-7-trifluoromethylindazole, 21
Show/Hide
|
C22H13ClF6N2
|
1
|
1 |
EC50 = 15460 nM
|
|
|
CP0128009
|
3-Methyl-2-[3'-(methylsulfonyl)biphenyl-4-yl]-5-(trifluoromethyl)-quinoxaline
Show/Hide
|
C23H17F3N2O2S
|
1
|
1 |
EC50 > 1000 nM
|
|
|