Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(5-((3-(8-(trifluoromethyl)quinolin-4-yl)phenyl)methylamino)naphthalen-1-yl)acetic acid
    Show/Hide
 PubChem ID
CID: 24936148
SID: 53834225
Canonical SMILES
OC(=O)Cc1cccc2c(NCc3cccc(c3)-c3ccnc4c(cccc34)C(F)(F)F)cccc12
    Show/Hide
Compound Formula C29H21F3N2O2
Compound Structure
Protein Name
 Protein Info 
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 622 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM