Brief Information of the Compound and Protein
Compound Name
3-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline
    Show/Hide
PubChem ID
CID: 25100150
SID: 56419846
Canonical SMILES
Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(c2)S(C)(=O)=O)c1)C(F)(F)F
    Show/Hide
Compound Formula C24H18F3NO3S
Compound Structure
Protein Name
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
>
Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
EC50 = 183 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.4 nM