Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(3-(3-chloro-5-(methylsulfonyl)phenoxy)phenyl)-8-(trifluoromethyl)quinoline-3-carboxamide
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 PubChem ID
CID: 46225196
Canonical SMILES
CS(=O)(=O)c1cc(Cl)cc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(N)=O)c1
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Compound Formula C24H16ClF3N2O4S
Compound Structure
Protein Name
 Protein Info 
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 460 nM
   TI
   LI
   LO
   TS
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 1700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 61 nM