| Compound ID |
Compound Name |
Compound Formula |
|
CP0008077
|
(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
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|
C22H29FO5
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0083140
|
N,N-dimethyl-4-[(5S)-5-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-5H-chromeno[2,3-b]pyridin-2-yl]benzamide
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|
C27H25N5O3S
|
1
|
| 1 |
EC50 = 22.7 nM
|
|
|
|
CP0087252
|
2-[(9S)-3-hydroxy-9H-xanthen-9-yl]-2-methyl-N-(1,3-thiazol-2-yl)propanamide
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|
C20H18N2O3S
|
1
|
| 1 |
EC50 = 27.1 nM
|
|
|
|
CP0256572
|
(3S)-3-(3-fluoro-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
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|
C20H19FN2O2S
|
1
|
| 1 |
EC50 = 36.1 nM
|
|
|
|
CP0306287
|
(3S)-3-(3-bromo-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C19H18BrN3O2S
|
1
|
| 1 |
EC50 = 46.5 nM
|
|
|
|
CP0047174
|
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
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|
C21H28O5
|
2
|
| 1 |
EC50 = 57.4 nM
|
|
|
| 2 |
EC50 = 64 nM
|
|
|
|
CP0716109
|
[(5S)-2-[4-[(Ethylmethylamino)carbonyl]-3-fluorophenyl]-alpha,alpha-dimethyl-N-1,3,4-thiadiazol-2-yl-5H-[1]benzopyrano-[2,3-b]pyridin-5-acetamide
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|
C28H26FN5O3S
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0074372
|
2-[(9S)-3-hydroxy-9H-xanthen-9-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C19H17N3O3S
|
1
|
| 1 |
EC50 = 91.3 nM
|
|
|
|
CP0323511
|
2-[(5S)-2-[3-fluoro-4-(morpholine-4-carbonyl)phenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C29H26FN5O4S
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
|
CP0132652
|
2-methyl-2-[(5R)-2-(4-propan-2-yloxyphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C27H26N4O3S
|
1
|
| 1 |
EC50 = 107 nM
|
|
|
|
CP0256573
|
(3S)-3-(3-fluoro-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C19H18FN3O2S
|
1
|
| 1 |
EC50 = 131.8 nM
|
|
|
|
CP0073120
|
(3S)-3-(3-bromo-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
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|
C20H19BrN2O2S
|
1
|
| 1 |
EC50 = 142.2 nM
|
|
|
|
CP0078261
|
2-fluoro-N,N-dimethyl-4-[(5R)-5-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-5H-chromeno[2,3-b]pyridin-2-yl]benzamide
Show/Hide
|
C27H24FN5O3S
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0280531
|
3-(3-fluoro-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
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|
C20H19FN2O2S
|
1
|
| 1 |
EC50 = 197 nM
|
|
|
|
CP0087253
|
(3S)-3-(4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
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|
C20H20N2O2S
|
2
|
| 1 |
EC50 = 250.7 nM
|
|
|
| 2 |
EC50 = 251 nM
|
|
|
|
CP0145661
|
2-[(5S)-2-[3-chloro-4-(3,3-difluoropyrrolidine-1-carbonyl)phenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C29H24ClF2N5O3S
|
1
|
| 1 |
EC50 = 329 nM
|
|
|
|
CP0213088
|
2-[(5S)-2-[3-fluoro-4-(pyrrolidine-1-carbonyl)phenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C29H26FN5O3S
|
1
|
| 1 |
EC50 = 389 nM
|
|
|
|
CP0169235
|
2-[(5R)-2-(4-ethylphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C26H24N4O2S
|
1
|
| 1 |
EC50 = 732 nM
|
|
|
|
CP0297988
|
N-ethyl-N-methyl-4-[(5R)-5-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-5H-chromeno[2,3-b]pyridin-2-yl]benzamide
Show/Hide
|
C28H27N5O3S
|
1
|
| 1 |
EC50 = 740 nM
|
|
|
|
CP0210725
|
(3S)-3-(4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C19H19N3O2S
|
1
|
| 1 |
EC50 = 748.5 nM
|
|
|
|
CP0093346
|
2-methyl-2-[(5R)-2-(4-propylphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C27H26N4O2S
|
1
|
| 1 |
EC50 = 823 nM
|
|
|
|
CP0132651
|
2-[(5S)-2-(3-fluoro-4-propan-2-yloxyphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C27H25FN4O3S
|
1
|
| 1 |
EC50 = 876 nM
|
|
|
|
CP0237984
|
2-[(5S)-2-(4-acetylphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C26H22N4O3S
|
1
|
| 1 |
EC50 = 1097 nM
|
|
|
|
CP0286694
|
2,2-dimethyl-3,3-diphenyl-N-(1,3-thiazol-2-yl)propanamide
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|
C20H20N2OS
|
1
|
| 1 |
EC50 = 1357 nM
|
|
|
|
CP0335635
|
2-[(5S)-2-[4-(3,3-difluoropyrrolidine-1-carbonyl)-3-fluorophenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C29H24F3N5O3S
|
1
|
| 1 |
EC50 = 1989 nM
|
|
|
|
CP0234749
|
(3S)-3-(3-acetyl-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
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|
C22H22N2O3S
|
1
|
| 1 |
EC50 = 2325 nM
|
|
|
|
CP0210668
|
2-chloro-N-ethyl-N-methyl-4-[(5R)-5-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-5H-chromeno[2,3-b]pyridin-2-yl]benzamide
Show/Hide
|
C28H26ClN5O3S
|
1
|
| 1 |
EC50 = 2403 nM
|
|
|
|
CP0280530
|
3-(4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
EC50 = 2579 nM
|
|
|
|
CP0303488
|
(3R)-3-(4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0306286
|
3-(2-fluoro-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
Show/Hide
|
C20H19FN2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0047027
|
(3R)-3-(3-fluoro-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
Show/Hide
|
C20H19FN2O2S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0047028
|
(3S)-3-(3-cyano-4-hydroxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
Show/Hide
|
C21H19N3O2S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0286695
|
3-(4-methoxyphenyl)-2,2-dimethyl-3-phenyl-N-(1,3-thiazol-2-yl)propanamide
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|
C21H22N2O2S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0295884
|
(3S)-3-(4-hydroxy-3-methylphenyl)-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
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|
C20H21N3O2S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0083142
|
N,N-dimethyl-6-[9-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-9H-xanthen-3-yl]pyridine-3-carboxamide
Show/Hide
|
C27H25N5O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0083148
|
2-methyl-2-[(5S)-2-(4-methylphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C25H22N4O2S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0083149
|
2-methyl-2-[(5S)-2-phenyl-5H-chromeno[2,3-b]pyridin-5-yl]-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C24H20N4O2S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0093348
|
2-[(5S)-2-(4-acetyl-3-fluorophenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C26H21FN4O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0093349
|
2-[(5S)-2-(4-ethylsulfonylphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C26H24N4O4S2
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0093350
|
2-[(5R)-2-(4-methoxyphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C25H22N4O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0213090
|
2-[(5S)-2-(4-methoxyphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C25H22N4O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0236526
|
4-[(5S)-5-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-5H-chromeno[2,3-b]pyridin-2-yl]benzamide
Show/Hide
|
C25H21N5O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0304453
|
2-fluoro-N-methyl-4-[(5S)-5-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-5H-chromeno[2,3-b]pyridin-2-yl]benzamide
Show/Hide
|
C26H22FN5O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0314580
|
N,N-dimethyl-4-[9-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-9H-xanthen-3-yl]benzamide
Show/Hide
|
C28H26N4O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0323512
|
2-[(5S)-2-[3-fluoro-4-(piperidine-1-carbonyl)phenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C30H28FN5O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0335636
|
2-methyl-2-[(5S)-2-[4-(piperidine-1-carbonyl)phenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C30H29N5O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0335637
|
N,N-dimethyl-4-[(5R)-5-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-5H-chromeno[2,3-b]pyridin-2-yl]benzamide
Show/Hide
|
C27H25N5O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0335638
|
N-methyl-4-[(5S)-5-[2-methyl-1-oxo-1-(1,3,4-thiadiazol-2-ylamino)propan-2-yl]-5H-chromeno[2,3-b]pyridin-2-yl]benzamide
Show/Hide
|
C26H23N5O3S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0335640
|
2-methyl-2-[(5S)-2-(2-methylphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C25H22N4O2S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0338180
|
2-methyl-2-[(5S)-2-(3-methylphenyl)-5H-chromeno[2,3-b]pyridin-5-yl]-N-(1,3,4-thiadiazol-2-yl)propanamide
Show/Hide
|
C25H22N4O2S
|
1
|
| 1 |
EC50 > 5000 nM
|
|
|
|
CP0858705
|
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-propylpyridine-3-carboxylate
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|
C18H18ClFN2O2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0645863
|
(R)-Methyl 2-((1H-Tetrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
Show/Hide
|
C17H14ClFN6O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0790986
|
Methyl 2-((1H-Tetrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
Show/Hide
|
C17H14ClFN6O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0805098
|
Methyl 4-(2-Chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-propylpyridine-3-carboxylate
Show/Hide
|
C18H19ClN2O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0906869
|
Methyl 2-Butyl-4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methylpyridine-3-carboxylate
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|
C19H21ClN2O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0645725
|
Methyl 2-((1H-Imidazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
Show/Hide
|
C19H16ClFN4O2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0645727
|
Methyl 2-((1H-1,2,4-Triazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
Show/Hide
|
C18H15ClFN5O2
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
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CP0675470
|
Methyl 2-((1H-Pyrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
Show/Hide
|
C19H16ClFN4O2
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0675469
|
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-6-methyl-2-(trifluoromethyl)-1,4-dihydropyridine-3-carboxylate
Show/Hide
|
C16H11ClF4N2O2
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
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CP0683120
|
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,4-dihydro-2,6-dimethylpyridine-3-carboxylate
Show/Hide
|
C16H14ClFN2O2
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
