| Compound ID |
Compound Name |
Compound Formula |
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CP0404089
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-2,18-dimethoxy-13,13-dimethyl-6,9-dioxo-10-oxa-5,8-diazatetracyclo[15.5.3.12,5.020,24]hexacosa-1(23),17,19,21,24-pentaene-4-carboxamide
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C41H56N4O9S
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2
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| 1 |
EC50 = 0.2 nM
|
|
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| 2 |
EC50 = 0.3 nM
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CP0389077
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(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-2,18-dimethoxy-6,9-dioxo-10-oxa-5,8-diazatetracyclo[15.5.3.12,5.020,24]hexacosa-1(23),17,19,21,24-pentaene-4-carboxamide
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C39H52N4O9S
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2
|
| 1 |
EC50 = 0.3 nM
|
|
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| 2 |
EC50 = 0.5 nM
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CP0559951
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-2,17-dimethoxy-6,9-dioxo-10-oxa-5,8-diazatetracyclo[14.5.3.12,5.019,23]pentacosa-1(22),16,18,20,23-pentaene-4-carboxamide
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C38H50N4O9S
|
2
|
| 1 |
EC50 = 0.6 nM
|
|
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| 2 |
EC50 = 2 nM
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CP0427723
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]-2,18-dimethoxy-6,9-dioxo-10-oxa-5,8-diazatetracyclo[15.5.3.12,5.020,24]hexacosa-1(23),17,19,21,24-pentaene-4-carboxamide
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|
C40H54N4O9S
|
2
|
| 1 |
EC50 = 1 nM
|
|
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| 2 |
EC50 = 1.8 nM
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CP0153399
|
[(2R)-1,1,1-trifluoropropan-2-yl] N-[(1S)-2-[(2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yl)oxy-2-[[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]carbamate
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|
C37H45ClF3N5O9S
|
2
|
| 1 |
EC50 = 1 nM
|
|
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| 2 |
EC50 = 4.5 nM
|
|
|
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CP0427811
|
Asunaprevir
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|
C35H46ClN5O9S
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2
|
| 1 |
EC50 = 1.2 nM
|
|
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| 2 |
EC50 = 4 nM
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CP0404088
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-2,18-dimethoxy-12,12-dimethyl-6,9-dioxo-10-oxa-5,8-diazatetracyclo[15.5.3.12,5.020,24]hexacosa-1(23),17,19,21,24-pentaene-4-carboxamide
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|
C41H56N4O9S
|
2
|
| 1 |
EC50 = 1.8 nM
|
|
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| 2 |
EC50 = 2.2 nM
|
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CP0427810
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]-2,18-dimethoxy-13,13-dimethyl-6,9-dioxo-10-oxa-5,8-diazatetracyclo[15.5.3.12,5.020,24]hexacosa-1(23),17,19,21,24-pentaene-4-carboxamide
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|
C42H58N4O9S
|
2
|
| 1 |
EC50 = 3 nM
|
|
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| 2 |
EC50 = 6 nM
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|
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CP0484737
|
methyl (2R,4S,7S)-7-tert-butyl-4-[[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]carbamoyl]-2,19-dimethoxy-6,9-dioxo-10,17-dioxa-5,8,13-triazatetracyclo[16.5.3.12,5.021,25]heptacosa-1(24),18,20,22,25-pentaene-13-carboxylate
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|
C41H55N5O12S
|
2
|
| 1 |
EC50 = 4 nM
|
|
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| 2 |
EC50 = 18 nM
|
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CP0427725
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-2,16-dimethoxy-6,9-dioxo-10-oxa-5,8-diazatetracyclo[13.5.3.12,5.018,22]tetracosa-1(21),15,17,19,22-pentaene-4-carboxamide
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|
C37H48N4O9S
|
2
|
| 1 |
EC50 = 5 nM
|
|
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| 2 |
EC50 = 16 nM
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CP0416847
|
(2R,4S,7S)-7-tert-butyl-13-cyclopropyl-N-[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]-2,19-dimethoxy-6,9-dioxo-10,17-dioxa-5,8,13-triazatetracyclo[16.5.3.12,5.021,25]heptacosa-1(24),18,20,22,25-pentaene-4-carboxamide
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|
C42H57N5O10S
|
2
|
| 1 |
EC50 = 5 nM
|
|
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| 2 |
EC50 = 15 nM
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CP0567191
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-2-methoxy-6,9-dioxo-10,16-dioxa-5,8-diazatetracyclo[15.5.3.12,5.020,24]hexacosa-1(23),17(25),18,20(24),21-pentaene-4-carboxamide
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|
C37H48N4O9S
|
2
|
| 1 |
EC50 = 7 nM
|
|
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| 2 |
EC50 = 13 nM
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CP0548547
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]-2,18-dimethoxy-12,12-dimethyl-6,9-dioxo-10-oxa-5,8-diazatetracyclo[15.5.3.12,5.020,24]hexacosa-1(23),17,19,21,24-pentaene-4-carboxamide
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|
C42H58N4O9S
|
2
|
| 1 |
EC50 = 8 nM
|
|
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| 2 |
EC50 = 11 nM
|
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CP0416845
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-2,20-dimethoxy-6,9-dioxo-10-oxa-5,8-diazatetracyclo[17.5.3.12,5.022,26]octacosa-1(25),19,21,23,26-pentaene-4-carboxamide
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|
C41H56N4O9S
|
2
|
| 1 |
EC50 = 16 nM
|
|
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| 2 |
EC50 = 22 nM
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CP0416846
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]-2-methoxy-6,9-dioxo-10,16-dioxa-5,8-diazatetracyclo[15.5.3.12,5.020,24]hexacosa-1(23),17(25),18,20(24),21-pentaene-4-carboxamide
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|
C38H50N4O9S
|
2
|
| 1 |
EC50 = 27 nM
|
|
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| 2 |
EC50 = 35 nM
|
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CP0563690
|
tert-butyl N-[(2S)-1-[(2S,4R)-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]-4-methoxy-4-(6-methoxynaphthalen-2-yl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
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|
C37H50N4O9S
|
2
|
| 1 |
EC50 = 34 nM
|
|
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| 2 |
EC50 = 55 nM
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CP0404310
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-2,19-dimethoxy-6,9-dioxo-10-oxa-5,8-diazatetracyclo[16.5.3.12,5.021,25]heptacosa-1(24),18,20,22,25-pentaene-4-carboxamide
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|
C40H54N4O9S
|
2
|
| 1 |
EC50 = 35 nM
|
|
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| 2 |
EC50 = 96 nM
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CP0569246
|
tert-butyl N-[(2S)-1-[(2S,4R)-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]-4-(7-ethenyl-6-methoxynaphthalen-2-yl)-4-methoxypyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
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|
C39H52N4O9S
|
1
|
| 1 |
EC50 = 50 nM
|
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CP0908995
|
(13R,15S,12S)-12-(tert-butyl)-N-((1S,2R)-2-((cyclopropylsulfonyl)carbamoyl)-[1,1'-bi(cyclopropan)]-2-yl)-13,26-dimethoxy-6-methyl-10,13-dioxo-9-oxa-6,11-diaza-1(3,1)-pyrrolidina-2(2,7)-naphthalenacyclotridecaphane-15-carboxamide
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|
C40H55N5O10S
|
2
|
| 1 |
EC50 = 52 nM
|
|
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| 2 |
EC50 = 69 nM
|
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CP0427803
|
(2R,4S,7S)-7-tert-butyl-N-[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]-2,19-dimethoxy-6,9-dioxo-13-propan-2-yl-10,17-dioxa-5,8,13-triazatetracyclo[16.5.3.12,5.021,25]heptacosa-1(24),18,20,22,25-pentaene-4-carboxamide
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|
C42H59N5O10S
|
2
|
| 1 |
EC50 = 63 nM
|
|
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| 2 |
EC50 = 130 nM
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CP0536858
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tert-butyl N-[(2S)-1-[(2S,4R)-2-[[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]carbamoyl]-4-methoxy-4-(6-methoxynaphthalen-2-yl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
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|
C38H52N4O9S
|
2
|
| 1 |
EC50 = 244 nM
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|
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| 2 |
EC50 = 253 nM
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CP0404311
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(1,1,1-trifluoro-2-methylpropan-2-yl) N-[(2S)-1-[(2S,4R)-2-[[(1R,2S)-2-cyclopropyl-1-(cyclopropylsulfonylcarbamoyl)cyclopropyl]carbamoyl]-4-methoxy-4-(6-methoxynaphthalen-2-yl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
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|
C38H49F3N4O9S
|
2
|
| 1 |
EC50 = 302 nM
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| 2 |
EC50 = 320 nM
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