| Compound ID |
Compound Name |
Compound Formula |
|
CP0416001
|
5-(15-fluoro-6-oxo-7,10-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2,4,11(16),12,14-hexaen-4-yl)-2-(4-fluorophenyl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
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|
C33H26F2N4O5S
|
8
|
| 1 |
EC50 = 0.61 nM
|
|
|
| 2 |
EC50 = 0.62 nM
|
|
|
| 3 |
EC50 = 1.3 nM
|
|
|
| 4 |
EC50 = 1.5 nM
|
|
|
| 5 |
EC50 = 2.2 nM
|
|
|
| 6 |
EC50 = 6.4 nM
|
|
|
| 7 |
EC50 = 9.8 nM
|
|
|
| 8 |
EC50 = 11 nM
|
|
|
|
CP0136716
|
2-(4-fluorophenyl)-5-(15-fluoro-3,8,10-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,8,11(16),12,14-octaen-4-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
Show/Hide
|
C32H23F2N5O4S
|
11
|
| 1 |
EC50 = 0.63 nM
|
|
|
| 2 |
EC50 = 0.68 nM
|
|
|
| 3 |
EC50 = 1 nM
|
|
|
| 4 |
EC50 = 1.4 nM
|
|
|
| 5 |
EC50 = 2 nM
|
|
|
| 6 |
EC50 = 2.4 nM
|
|
|
| 7 |
EC50 = 3.1 nM
|
|
|
| 8 |
EC50 = 3.2 nM
|
|
|
| 9 |
EC50 = 3.3 nM
|
|
|
| 10 |
EC50 = 3.4 nM
|
|
|
| 11 |
EC50 = 16 nM
|
|
|
|
CP0204250
|
US9243002, 85
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|
C33H26F2N4O4S
|
12
|
| 1 |
EC50 = 0.86 nM
|
|
|
| 2 |
EC50 = 1.1 nM
|
|
|
| 3 |
EC50 = 1.2 nM
|
|
|
| 4 |
EC50 = 2.1 nM
|
|
|
| 5 |
EC50 = 2.7 nM
|
|
|
| 6 |
EC50 = 3 nM
|
|
|
| 7 |
EC50 = 3.3 nM
|
|
|
| 8 |
EC50 = 5.7 nM
|
|
|
| 9 |
EC50 = 6 nM
|
|
|
| 10 |
EC50 = 6.5 nM
|
|
|
| 11 |
EC50 = 8.4 nM
|
|
|
| 12 |
EC50 = 13 nM
|
|
|
|
CP0136717
|
2-(4-fluorophenyl)-5-(15-fluoro-3,8,10-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,11(16),12,14-heptaen-4-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
Show/Hide
|
C32H25F2N5O4S
|
11
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
EC50 = 1 nM
|
|
|
| 3 |
EC50 = 1.1 nM
|
|
|
| 4 |
EC50 = 1.8 nM
|
|
|
| 5 |
EC50 = 2.9 nM
|
|
|
| 6 |
EC50 = 3.1 nM
|
|
|
| 7 |
EC50 = 5.3 nM
|
|
|
| 8 |
EC50 = 5.7 nM
|
|
|
| 9 |
EC50 = 6.4 nM
|
|
|
| 10 |
EC50 = 7.6 nM
|
|
|
| 11 |
EC50 = 46 nM
|
|
|
|
CP0069138
|
US9243002, 82
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|
C33H24F2N4O4S
|
11
|
| 1 |
EC50 = 0.95 nM
|
|
|
| 2 |
EC50 = 1.2 nM
|
|
|
| 3 |
EC50 = 2.6 nM
|
|
|
| 4 |
EC50 = 2.9 nM
|
|
|
| 5 |
EC50 = 3.5 nM
|
|
|
| 6 |
EC50 = 4.8 nM
|
|
|
| 7 |
EC50 = 5.5 nM
|
|
|
| 8 |
EC50 = 6.3 nM
|
|
|
| 9 |
EC50 = 6.7 nM
|
|
|
| 10 |
EC50 = 11 nM
|
|
|
| 11 |
EC50 = 30 nM
|
|
|
|
CP0440237
|
US9243002, 72
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|
C34H28F2N4O4S
|
8
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
EC50 = 1.2 nM
|
|
|
| 3 |
EC50 = 1.5 nM
|
|
|
| 4 |
EC50 = 1.9 nM
|
|
|
| 5 |
EC50 = 6.5 nM
|
|
|
| 6 |
EC50 = 6.8 nM
|
|
|
| 7 |
EC50 = 16 nM
|
|
|
| 8 |
EC50 = 26 nM
|
|
|
|
CP0339286
|
US9265773, 2
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|
C32H24F2N4O5S
|
10
|
| 1 |
EC50 = 1.1 nM
|
|
|
| 2 |
EC50 = 1.2 nM
|
|
|
| 3 |
EC50 = 1.6 nM
|
|
|
| 4 |
EC50 = 1.8 nM
|
|
|
| 5 |
EC50 = 2.2 nM
|
|
|
| 6 |
EC50 = 2.4 nM
|
|
|
| 7 |
EC50 = 2.7 nM
|
|
|
| 8 |
EC50 = 3.9 nM
|
|
|
| 9 |
EC50 = 7.3 nM
|
|
|
| 10 |
EC50 = 27 nM
|
|
|
|
CP0433959
|
6-(ethylamino)-2-(4-fluorophenyl)-5-[4-methoxy-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-N-methyl-1-benzofuran-3-carboxamide
Show/Hide
|
C33H30FN5O4
|
4
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
EC50 = 2.3 nM
|
|
|
| 3 |
EC50 = 3.6 nM
|
|
|
| 4 |
EC50 = 12 nM
|
|
|
|
CP0416000
|
US9243002, 99
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|
C35H30F2N4O4S
|
8
|
| 1 |
EC50 = 1.9 nM
|
|
|
| 2 |
EC50 = 2 nM
|
|
|
| 3 |
EC50 = 3.5 nM
|
|
|
| 4 |
EC50 = 3.8 nM
|
|
|
| 5 |
EC50 = 5.2 nM
|
|
|
| 6 |
EC50 = 13 nM
|
|
|
| 7 |
EC50 = 26 nM
|
|
|
| 8 |
EC50 = 42 nM
|
|
|
|
CP0422209
|
US9243002, 88
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|
C32H24F2N4O4S
|
8
|
| 1 |
EC50 = 2.2 nM
|
|
|
| 2 |
EC50 = 2.7 nM
|
|
|
| 3 |
EC50 = 3 nM
|
|
|
| 4 |
EC50 = 3.9 nM
|
|
|
| 5 |
EC50 = 5.1 nM
|
|
|
| 6 |
EC50 = 8.5 nM
|
|
|
| 7 |
EC50 = 9.5 nM
|
|
|
| 8 |
EC50 = 34 nM
|
|
|
|
CP0408720
|
(3S,5S)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3-(methylsulfonylmethyl)-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C23H25FN2O7S2
|
4
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 7 nM
|
|
|
| 3 |
EC50 = 10 nM
|
|
|
| 4 |
EC50 = 18 nM
|
|
|
|
CP0438358
|
(5S)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C21H21FN2O5S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0440792
|
2-(4-fluorophenyl)-N,5-dimethyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
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|
C22H23FN2O4S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0547800
|
(3S,5S)-8-(4-fluorophenyl)-3-(hydroxymethyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C22H23FN2O6S
|
4
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 6 nM
|
|
|
| 3 |
EC50 = 9 nM
|
|
|
| 4 |
EC50 = 12 nM
|
|
|
|
CP0556656
|
(2S)-14-(4-fluorophenyl)-N,2-dimethyl-9-methylsulfonyl-13-oxa-3,4,5,9-tetrazatetracyclo[8.7.0.03,7.012,16]heptadeca-1(10),4,6,11,14,16-hexaene-15-carboxamide
Show/Hide
|
C22H20FN5O4S
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0434454
|
2-(4-fluorophenyl)-N-methyl-5-[3-[(1-pyridin-2-ylcyclopropyl)carbamoyl]phenyl]-1-benzofuran-3-carboxamide
Show/Hide
|
C31H24FN3O3
|
4
|
| 1 |
EC50 = 3.8 nM
|
|
|
| 2 |
EC50 = 36 nM
|
|
|
| 3 |
EC50 = 75 nM
|
|
|
| 4 |
EC50 = 515 nM
|
|
|
|
CP0408709
|
(5R)-2-(4-fluorophenyl)-N,5-dimethyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
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|
C22H23FN2O4S
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0410297
|
5-(4-fluorophenyl)-N-methyl-15-methylsulfonyl-4-oxa-15-azatricyclo[7.6.0.03,7]pentadeca-1,3(7),5,8-tetraene-6-carboxamide
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|
C22H23FN2O4S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0427229
|
(5S)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3-oxo-4,5-dihydro-2H-furo[3,2-h][1,4]benzodiazepine-7-carboxamide
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|
C21H20FN3O5S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0444355
|
2-(4-fluorophenyl)-3-(1H-imidazol-2-yl)-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine
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|
C22H20FN3O3S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0469386
|
6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-N-methyl-5-[3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-1-benzofuran-3-carboxamide
Show/Hide
|
C33H30FN5O5S
|
4
|
| 1 |
EC50 = 5.4 nM
|
|
|
| 2 |
EC50 = 7.7 nM
|
|
|
| 3 |
EC50 = 8.8 nM
|
|
|
| 4 |
EC50 = 44 nM
|
|
|
|
CP0434455
|
2-(4-fluorophenyl)-6-[2-hydroxyethyl(methylsulfonyl)amino]-N-methyl-5-[3-[(1-phenylcyclopropyl)carbamoyl]phenyl]-1-benzofuran-3-carboxamide
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|
C35H32FN3O6S
|
4
|
| 1 |
EC50 = 5.7 nM
|
|
|
| 2 |
EC50 = 6.2 nM
|
|
|
| 3 |
EC50 = 8.6 nM
|
|
|
| 4 |
EC50 = 64 nM
|
|
|
|
CP0545950
|
14-(4-fluorophenyl)-N,2-dimethyl-9-methylsulfonyl-13-oxa-3,4,5,9-tetrazatetracyclo[8.7.0.03,7.012,16]heptadeca-1(10),4,6,11,14,16-hexaene-15-carboxamide
Show/Hide
|
C22H20FN5O4S
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0428766
|
5-[3-chloro-4-methoxy-5-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide
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|
C34H31ClFN5O6S
|
1
|
| 1 |
EC50 = 6.6 nM
|
|
|
|
CP0410299
|
8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3-(methylsulfonylmethyl)-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C23H25FN2O7S2
|
3
|
| 1 |
EC50 = 7 nM
|
|
|
| 2 |
EC50 = 17 nM
|
|
|
| 3 |
EC50 = 64 nM
|
|
|
|
CP0547797
|
(10R,12R)-5-(4-fluorophenyl)-N-methyl-15-methylsulfonyl-4-oxa-15-azatetracyclo[7.6.0.03,7.010,12]pentadeca-1(9),2,5,7-tetraene-6-carboxamide
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|
C22H21FN2O4S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0561428
|
2-(2-fluorophenyl)-N,5-dimethyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
|
C22H23FN2O4S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0545948
|
2-(2,4-difluorophenyl)-N,5-dimethyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
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|
C22H22F2N2O4S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0563700
|
8-(4-fluorophenyl)-N,3,5-trimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C22H23FN2O5S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0553546
|
6-[ethyl(methylsulfonyl)amino]-5-[3-fluoro-4-methoxy-5-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide
Show/Hide
|
C34H31F2N5O6S
|
1
|
| 1 |
EC50 = 8.8 nM
|
|
|
|
CP0396138
|
5-(4-fluorophenyl)-N-methyl-15-methylsulfonyl-4-oxa-15-azatetracyclo[7.6.0.03,7.010,12]pentadeca-1(9),2,5,7-tetraene-6-carboxamide
Show/Hide
|
C22H21FN2O4S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0471851
|
5-[3,4-difluoro-5-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide
Show/Hide
|
C33H28F3N5O5S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0410278
|
14-(4-fluorophenyl)-N,2-dimethyl-9-methylsulfonyl-13-oxa-3,4,5,6,9-pentazatetracyclo[8.7.0.03,7.012,16]heptadeca-1(10),4,6,11,14,16-hexaene-15-carboxamide
Show/Hide
|
C21H19FN6O4S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0427222
|
8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C21H21FN2O5S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0389215
|
HCV 796
Show/Hide
|
C22H23FN2O5S
|
4
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
EC50 = 19 nM
|
|
|
| 3 |
EC50 = 21 nM
|
|
|
| 4 |
EC50 = 72 nM
|
|
|
|
CP0422901
|
8-(4-fluorophenyl)-3-(hydroxymethyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C22H23FN2O6S
|
4
|
| 1 |
EC50 = 12 nM
|
|
|
| 2 |
EC50 = 20 nM
|
|
|
| 3 |
EC50 = 32 nM
|
|
|
| 4 |
EC50 = 62 nM
|
|
|
|
CP0410283
|
(3R,5S)-8-(4-fluorophenyl)-3-(hydroxymethyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C22H23FN2O6S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0410286
|
(5S)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonylspiro[2,5-dihydrofuro[3,2-h][4,1]benzoxazepine-3,1'-cyclopropane]-7-carboxamide
Show/Hide
|
C23H23FN2O5S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0545952
|
(3R,5S)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3-(methylsulfonylmethyl)-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
|
C23H25FN2O7S2
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0558815
|
(5S)-8-(4-fluorophenyl)-N,4,5-trimethyl-1-methylsulfonyl-3-oxo-2,5-dihydrofuro[3,2-h][1,4]benzodiazepine-7-carboxamide
Show/Hide
|
C22H22FN3O5S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0533410
|
6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-5-[4-methoxy-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-N-methyl-1-benzofuran-3-carboxamide
Show/Hide
|
C34H32FN5O6S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0410280
|
8-(4-fluorophenyl)-N,4,5-trimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][1,4]benzodiazepine-7-carboxamide
Show/Hide
|
C22H24FN3O4S
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0556654
|
2-[4-(4-fluorophenoxy)phenyl]-N,5-dimethyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
|
C28H27FN2O5S
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0408747
|
8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3-oxo-4,5-dihydro-2H-furo[3,2-h][1,4]benzodiazepine-7-carboxamide
Show/Hide
|
C21H20FN3O5S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0520422
|
methyl N-ethyl-N-[2-(4-fluorophenyl)-5-[4-methoxy-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-3-(methylcarbamoyl)-1-benzofuran-6-yl]carbamate
Show/Hide
|
C35H32FN5O6
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0410296
|
2-(4-fluorophenyl)-N,5-dimethyl-9-methylsulfonyl-7,8-dihydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
|
C22H21FN2O4S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0533411
|
6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-5-[4-methoxy-3-methyl-5-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-N-methyl-1-benzofuran-3-carboxamide
Show/Hide
|
C35H34FN5O6S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0408325
|
2-(4-fluorophenyl)-N-methyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
|
C21H21FN2O4S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0475810
|
8-(4-fluorophenyl)-N,4,5-trimethyl-1-methylsulfonyl-3-oxo-2,5-dihydrofuro[3,2-h][1,4]benzodiazepine-7-carboxamide
Show/Hide
|
C22H22FN3O5S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0410287
|
8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonylspiro[2,5-dihydrofuro[3,2-h][4,1]benzoxazepine-3,1'-cyclopropane]-7-carboxamide
Show/Hide
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C23H23FN2O5S
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1
|
| 1 |
EC50 = 19 nM
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CP0440794
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8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-2-(methylsulfonylmethyl)-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
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C23H25FN2O7S2
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4
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| 1 |
EC50 = 19 nM
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| 2 |
EC50 = 51 nM
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| 3 |
EC50 = 70 nM
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| 4 |
EC50 = 134 nM
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CP0561427
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2-(4-fluorophenyl)-N-methyl-9-methylsulfonylspiro[7,8-dihydro-6H-furo[3,2-h][1]benzazepine-5,1'-cyclopropane]-3-carboxamide
Show/Hide
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C23H23FN2O4S
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1
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| 1 |
EC50 = 20 nM
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CP0559673
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6-[ethyl-(2,2,2-trifluoroacetyl)amino]-2-(4-fluorophenyl)-5-[4-methoxy-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-N-methyl-1-benzofuran-3-carboxamide
Show/Hide
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C35H29F4N5O5
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1
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| 1 |
EC50 = 20 nM
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CP0412295
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propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-4-bromo-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Show/Hide
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C21H26BrFN3O9P
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7
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| 1 |
EC50 = 21 nM
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| 2 |
EC50 = 24 nM
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| 3 |
EC50 = 30 nM
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| 4 |
EC50 = 38 nM
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| 5 |
EC50 = 46 nM
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| 6 |
EC50 = 55 nM
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| 7 |
EC50 = 180 nM
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CP0519248
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2-(4-fluorophenyl)-6-[2-hydroxyethyl(methylsulfonyl)amino]-N-methyl-5-[3-[(1-pyridin-2-ylcyclopropyl)carbamoyl]phenyl]-1-benzofuran-3-carboxamide
Show/Hide
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C34H31FN4O6S
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4
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| 1 |
EC50 = 22 nM
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| 2 |
EC50 = 35 nM
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| 3 |
EC50 = 52 nM
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| 4 |
EC50 = 385 nM
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CP0408706
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(3S,5R)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3-(methylsulfonylmethyl)-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
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C23H25FN2O7S2
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1
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| 1 |
EC50 = 24 nM
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CP0408319
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2-(4-fluorophenyl)-N-methyl-5-methylidene-9-methylsulfonyl-7,8-dihydro-6H-furo[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
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C22H21FN2O4S
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1
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| 1 |
EC50 = 26 nM
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CP0568914
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5-(4-fluorophenyl)-N-methyl-16-methylsulfonyl-4-oxa-16-azatricyclo[7.7.0.03,7]hexadeca-1,3(7),5,8-tetraene-6-carboxamide
Show/Hide
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C23H25FN2O4S
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1
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| 1 |
EC50 = 26 nM
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CP0563693
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2-(4-fluorophenyl)-N-methoxy-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
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C21H21FN2O5S
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1
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| 1 |
EC50 = 31 nM
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CP0410298
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8-(4-fluorophenyl)-2-(hydroxymethyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
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C22H23FN2O6S
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4
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| 1 |
EC50 = 33 nM
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| 2 |
EC50 = 53 nM
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| 3 |
EC50 = 117 nM
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| 4 |
EC50 = 141 nM
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CP0031380
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CHEBI:85083
Show/Hide
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C22H29FN3O9P
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9
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| 1 |
EC50 = 34 nM
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| 2 |
EC50 = 43 nM
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| 3 |
EC50 = 44 nM
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| 4 |
EC50 = 58 nM
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| 5 |
EC50 = 61 nM
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| 6 |
EC50 = 64 nM
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| 7 |
EC50 = 155 nM
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| 8 |
EC50 = 230 nM
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| 9 |
EC50 = 300 nM
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CP0471850
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6-[acetyl(ethyl)amino]-2-(4-fluorophenyl)-5-[4-methoxy-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-N-methyl-1-benzofuran-3-carboxamide
Show/Hide
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C35H32FN5O5
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1
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| 1 |
EC50 = 35 nM
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CP0034787
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1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BENZOTHIADIAZIN-3-YL)-6-FLUORO-4-HYDROXYQUINOLIN-2(1H)-ONE
Show/Hide
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C21H18FN3O4S
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1
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| 1 |
EC50 = 38 nM
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CP0410277
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(2R)-14-(4-fluorophenyl)-N,2-dimethyl-9-methylsulfonyl-13-oxa-3,4,5,9-tetrazatetracyclo[8.7.0.03,7.012,16]heptadeca-1(10),4,6,11,14,16-hexaene-15-carboxamide
Show/Hide
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C22H20FN5O4S
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1
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| 1 |
EC50 = 38 nM
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CP0475811
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8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-2,3,4,5-tetrahydrofuro[3,2-h][1,4]benzodiazepine-7-carboxamide
Show/Hide
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C21H22FN3O4S
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1
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| 1 |
EC50 = 43 nM
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CP0562548
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(5S)-2-(4-fluorophenyl)-N,5-dimethyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
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C22H23FN2O4S
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1
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| 1 |
EC50 = 46 nM
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CP0408748
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2-(4-fluoro-2-methoxyphenyl)-N,5-dimethyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
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C23H25FN2O5S
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1
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| 1 |
EC50 = 56 nM
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CP0408705
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(5R)-8-(4-fluorophenyl)-N,4,5-trimethyl-1-methylsulfonyl-3-oxo-2,5-dihydrofuro[3,2-h][1,4]benzodiazepine-7-carboxamide
Show/Hide
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C22H22FN3O5S
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1
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| 1 |
EC50 = 59 nM
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CP0410284
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(3S,5R)-8-(4-fluorophenyl)-3-(hydroxymethyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
Show/Hide
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C22H23FN2O6S
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1
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| 1 |
EC50 = 69 nM
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CP0556657
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9-cyclopropylsulfonyl-2-(4-fluorophenyl)-N-methyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
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C23H23FN2O4S
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1
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| 1 |
EC50 = 73 nM
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CP0410292
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14-(4-fluorophenyl)-N,2-dimethyl-9-methylsulfonyl-13-oxa-3,6,9-triazatetracyclo[8.7.0.03,7.012,16]heptadeca-1(10),4,6,11,14,16-hexaene-15-carboxamide
Show/Hide
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C23H21FN4O4S
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1
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| 1 |
EC50 = 74 nM
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CP0440791
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2-(4-fluorophenyl)-N-methyl-9-methylsulfonyl-5-oxo-7,8-dihydro-6H-furo[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
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C21H19FN2O5S
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1
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| 1 |
EC50 = 78 nM
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CP0943088
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(S)-2-Amino-3-methyl-butyric acid (2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-[(S)-((S)-1-isopropoxycarbonyl-ethylamino)-(naphthalen-1-yloxy)-phosphoryloxymethyl]-tetrahydro-furan-3-yl ester
Show/Hide
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C30H37BrClN4O10P
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2
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| 1 |
EC50 = 94 nM
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| 2 |
EC50 = 99 nM
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CP0869030
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(S)-isopropyl 2-((S)-(((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(3-methoxyphenoxy)phosphorylamino)propanoate
Show/Hide
|
C22H28BrClN3O10P
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2
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| 1 |
EC50 = 98 nM
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| 2 |
EC50 = 127 nM
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CP0954080
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(S)-isopropyl 2-((S)-(((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(naphthalen-1-yloxy)phosphorylamino)propanoate
Show/Hide
|
C25H28BrClN3O9P
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2
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| 1 |
EC50 = 106 nM
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| 2 |
EC50 = 139 nM
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CP0408708
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2-(4-fluorophenyl)-5-hydroxy-N-methyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
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C21H21FN2O5S
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1
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| 1 |
EC50 = 107 nM
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CP0475808
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5-(4-fluorophenyl)-N,10-dimethyl-14-methylsulfonyl-3,4,14-triazatricyclo[7.5.0.03,7]tetradeca-1,4,6,8-tetraene-6-carboxamide
Show/Hide
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C21H23FN4O3S
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1
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| 1 |
EC50 = 109 nM
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CP0870591
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(S)-Isopropyl 2-(((S)-(((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate
Show/Hide
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C21H26BrClN3O9P
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2
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| 1 |
EC50 = 114 nM
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| 2 |
EC50 = 147 nM
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CP0412290
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propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-4-bromo-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Show/Hide
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C21H26BrFN3O9P
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7
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| 1 |
EC50 = 120 nM
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| 2 |
EC50 = 160 nM
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| 3 |
EC50 = 170 nM
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| 4 |
EC50 = 210 nM
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| 5 |
EC50 = 230 nM
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| 6 |
EC50 = 700 nM
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| 7 |
EC50 = 3600 nM
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CP0250399
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1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]-thiadiazin-3-yl)-4-hydroxy-1H-quinolin-2-one
Show/Hide
|
C21H19N3O4S
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1
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| 1 |
EC50 = 152 nM
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CP0958083
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(S)-2-Amino-3-methyl-butyric acid (2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-[(S)-((S)-1-isopropoxycarbonyl-ethylamino)-phenoxy-phosphoryloxymethyl]-tetrahydro-furan-3-yl ester
Show/Hide
|
C26H35BrClN4O10P
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2
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| 1 |
EC50 = 156 nM
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| 2 |
EC50 = 167 nM
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CP0255446
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6-Amino-1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-
Show/Hide
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C21H20N4O4S
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1
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| 1 |
EC50 = 157 nM
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CP0561438
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methyl 2-(4-fluorophenyl)-3-(methylcarbamoyl)-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-9-carboxylate
Show/Hide
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C22H21FN2O4
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1
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| 1 |
EC50 = 164 nM
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CP0563553
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6-[dimethylcarbamoyl(ethyl)amino]-2-(4-fluorophenyl)-5-[4-methoxy-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]phenyl]-N-methyl-1-benzofuran-3-carboxamide
Show/Hide
|
C36H35FN6O5
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1
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| 1 |
EC50 = 165 nM
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CP0299364
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3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-6-methyl-1-(3-methylbutyl)-1H-quinolin-2-one
Show/Hide
|
C22H23N3O4S
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1
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| 1 |
EC50 = 180 nM
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CP0560073
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5-(4-fluorophenyl)-N,14-dimethyl-10-methylsulfonyl-3,6,10-triazatricyclo[7.5.0.03,7]tetradeca-1,4,6,8-tetraene-4-carboxamide
Show/Hide
|
C21H23FN4O3S
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1
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| 1 |
EC50 = 182 nM
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CP0099391
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1-cyclobutylmethyl-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-1H-quinolin-2-one
Show/Hide
|
C21H19N3O4S
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1
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| 1 |
EC50 = 241 nM
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CP0334938
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3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-6-fluoro-4-hydroxy-1-(3-methyl-butyl)-1H-quinolin-2-one
Show/Hide
|
C21H20FN3O4S
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1
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| 1 |
EC50 = 261 nM
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CP0223342
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ethyl 2-[[3-(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxoquinolin-6-yl]amino]acetate
Show/Hide
|
C25H28N4O6S
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1
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| 1 |
EC50 = 265 nM
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CP0255452
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6-amino-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-1H-quinolin-2-one
Show/Hide
|
C21H22N4O4S
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1
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| 1 |
EC50 = 274 nM
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CP0255450
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4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-6-yloxy]acetonitrile
Show/Hide
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C23H22N4O5S
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1
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| 1 |
EC50 = 298 nM
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CP0545954
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2-(4-fluorophenyl)-N-hydroxy-N-methyl-9-methylsulfonyl-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine-3-carboxamide
Show/Hide
|
C21H21FN2O5S
|
1
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| 1 |
EC50 = 298 nM
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CP0954790
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(S)-ethyl 2-((S)-(((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate
Show/Hide
|
C20H24BrClN3O9P
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2
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| 1 |
EC50 = 298 nM
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| 2 |
EC50 = 301 nM
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CP0562549
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2-(4-fluorophenyl)-N-methyl-7-methylsulfonyl-5,6-dihydrofuro[3,2-f]indole-3-carboxamide
Show/Hide
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C19H17FN2O4S
|
1
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| 1 |
EC50 = 304 nM
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CP0954081
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(2S)-2-((((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propyl isobutyrate
Show/Hide
|
C22H28BrClN3O9P
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2
|
| 1 |
EC50 = 317 nM
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| 2 |
EC50 = 455 nM
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CP0250386
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1-(3,3-dimethylbutyl)-3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-6-(2-hydroxyethylamino)-1H-quinolin-2-one
Show/Hide
|
C24H28N4O5S
|
1
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| 1 |
EC50 = 370 nM
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CP0334939
|
3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-5-fluoro-4-hydroxy-1-(3-methylbutyl)-1H-quinolin-2-one
Show/Hide
|
C21H20FN3O4S
|
1
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| 1 |
EC50 = 381 nM
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CP0956913
|
(2S)-1-methoxypropan-2-yl 2-((((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate
Show/Hide
|
C22H28BrClN3O10P
|
2
|
| 1 |
EC50 = 387 nM
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| 2 |
EC50 = 414 nM
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CP0250390
|
3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-1-furan-3-ylmethyl-4-hydroxy-1H-quinolin-2-one
Show/Hide
|
C21H15N3O5S
|
1
|
| 1 |
EC50 = 389 nM
|
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CP0959694
|
Isopropyl ((R)-(((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
Show/Hide
|
C21H26BrClN3O9P
|
2
|
| 1 |
EC50 = 415 nM
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|
| 2 |
EC50 = 515 nM
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CP0040918
|
3-(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)quinolin-2-one
Show/Hide
|
C21H21N3O4S
|
1
|
| 1 |
EC50 = 417 nM
|
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CP0083396
|
1-Butyl-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1H-quinolin-2-one
Show/Hide
|
C20H19N3O4S
|
1
|
| 1 |
EC50 = 444 nM
|
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CP0561439
|
2-(4-fluorophenyl)-N-methyl-8-methylsulfonyl-6,7-dihydro-5H-furo[3,2-g]quinoline-3-carboxamide
Show/Hide
|
C20H19FN2O4S
|
1
|
| 1 |
EC50 = 451 nM
|
|
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CP0472079
|
propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-4-bromo-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Show/Hide
|
C21H26BrFN3O9P
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
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CP0334937
|
4-[3-(1,1-dioxo-1,4-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxo-1,2-dihydroquinolin-6-yloxy]acetamide
Show/Hide
|
C23H24N4O6S
|
1
|
| 1 |
EC50 = 511 nM
|
|
|
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CP0943089
|
(2S)-2-((((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propyl 3-methoxy-2-methylpropanoate
Show/Hide
|
C23H30BrClN3O10P
|
2
|
| 1 |
EC50 = 522 nM
|
|
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| 2 |
EC50 = 592 nM
|
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CP0545949
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(5R)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3-oxo-4,5-dihydro-2H-furo[3,2-h][1,4]benzodiazepine-7-carboxamide
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C21H20FN3O5S
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1
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| 1 |
EC50 = 586 nM
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CP0443803
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propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-bromo-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
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C22H27BrFN6O8P
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1
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| 1 |
EC50 = 600 nM
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CP0459465
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propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-bromo-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
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C21H27BrFN4O8P
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1
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| 1 |
EC50 = 600 nM
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CP0545951
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(5R)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonylspiro[2,5-dihydrofuro[3,2-h][4,1]benzoxazepine-3,1'-cyclopropane]-7-carboxamide
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C23H23FN2O5S
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1
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| 1 |
EC50 = 666 nM
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CP0408707
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(5R)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
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C21H21FN2O5S
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1
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| 1 |
EC50 = 686 nM
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CP0255468
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3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-phenyl-1Hquinolin-2-one
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C22H15N3O4S
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1
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| 1 |
EC50 = 774 nM
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CP0410281
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2-(4-fluorophenyl)-9-methylsulfonyl-3-(1H-1,2,4-triazol-5-yl)-5,6,7,8-tetrahydrofuro[3,2-h][1]benzazepine
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C21H19FN4O3S
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1
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| 1 |
EC50 = 850 nM
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CP0870589
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ethyl 2-((((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)-2-methylpropanoate
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C21H26BrClN3O9P
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2
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| 1 |
EC50 = 960 nM
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| 2 |
EC50 = 1170 nM
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CP0938648
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Isopropyl 2-(((((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)-2-methylpropanoate
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C22H28BrClN3O9P
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2
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| 1 |
EC50 = 1090 nM
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| 2 |
EC50 = 1380 nM
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CP0955950
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(S)-ethyl 2-((R)-(((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate
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C20H24BrClN3O9P
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2
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| 1 |
EC50 = 1190 nM
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| 2 |
EC50 = 1210 nM
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CP0255455
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6-chloro-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-1H-quinolin-2-one
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C21H20ClN3O4S
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1
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| 1 |
EC50 = 1204 nM
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CP0541325
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(3R,5R)-8-(4-fluorophenyl)-N,5-dimethyl-1-methylsulfonyl-3-(methylsulfonylmethyl)-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
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C23H25FN2O7S2
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1
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| 1 |
EC50 = 1208 nM
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CP0410279
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(3R,5R)-8-(4-fluorophenyl)-3-(hydroxymethyl)-N,5-dimethyl-1-methylsulfonyl-3,5-dihydro-2H-furo[3,2-h][4,1]benzoxazepine-7-carboxamide
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C22H23FN2O6S
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1
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| 1 |
EC50 = 1473 nM
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CP0324029
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2-[[3-(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxoquinolin-6-yl]amino]acetic acid
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C23H24N4O6S
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1
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| 1 |
EC50 = 2492 nM
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CP0866568
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(2S)-2-((((2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propyl 2-methoxyacetate
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C21H26BrClN3O10P
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2
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| 1 |
EC50 = 2500 nM
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| 2 |
EC50 = 3040 nM
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CP0378585
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2''-C-Mecytosine
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C10H15N3O5
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1
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| 1 |
EC50 = 2800 nM
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CP0472081
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4-amino-1-[(2R,3S,4R,5R)-3-bromo-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
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C9H11BrFN3O4
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1
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| 1 |
EC50 = 4000 nM
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CP0539604
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propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-bromo-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
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C22H27BrFN6O7P
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1
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| 1 |
EC50 = 7100 nM
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CP0412288
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2-amino-9-[(2R,3S,4R,5R)-3-bromo-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
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C10H11BrFN5O4
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1
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| 1 |
EC50 > 10000 nM
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CP0443802
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(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-bromo-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
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C10H11BrFN5O3
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1
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| 1 |
EC50 > 10000 nM
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CP0440790
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(10S,12S)-5-(4-fluorophenyl)-N-methyl-15-methylsulfonyl-4-oxa-15-azatetracyclo[7.6.0.03,7.010,12]pentadeca-1(9),2,5,7-tetraene-6-carboxamide
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C22H21FN2O4S
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1
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| 1 |
EC50 > 2000 nM
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CP0064491
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2'-C-Methyl-uridine-5'-triphosphate
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C10H17N2O15P3
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7
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| 1 |
IC50 = 25 nM
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| 2 |
IC50 = 47 nM
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| 3 |
IC50 = 63 nM
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| 4 |
IC50 = 70 nM
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| 5 |
IC50 = 97 nM
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| 6 |
IC50 = 190 nM
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| 7 |
IC50 = 36000 nM
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CP0048188
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((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
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C10H16FN2O14P3
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8
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| 1 |
IC50 = 96 nM
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| 2 |
IC50 = 130 nM
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| 3 |
IC50 = 180 nM
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| 4 |
IC50 = 290 nM
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| 5 |
IC50 = 380 nM
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| 6 |
IC50 = 430 nM
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| 7 |
IC50 = 570 nM
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| 8 |
IC50 = 7300 nM
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