Brief Information of the Compound and Protein
Compound Name
1-cyclobutylmethyl-3-(1,1-dioxo-1,2-dihydrobenzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-1H-quinolin-2-one
    Show/Hide
PubChem ID
CID: 135529534
SID: 15199704
Canonical SMILES
Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CC2CCC2)c2ccccc12
    Show/Hide
Compound Formula C21H19N3O4S
Compound Structure
Protein Name
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
EC50 = 241 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 49 nM