Brief Information of the Compound and Protein
Compound Name
1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]-thiadiazin-3-yl)-4-hydroxy-1H-quinolin-2-one
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PubChem ID
CID: 135421310
SID: 16563926
Canonical SMILES
Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2ccccc12
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Compound Formula C21H19N3O4S
Compound Structure
Protein Name
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
EC50 = 152 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM