Brief Information of the Compound and Protein
Compound Name
1-(2-CYCLOPROPYLETHYL)-3-(1,1-DIOXIDO-2H-1,2,4-BENZOTHIADIAZIN-3-YL)-6-FLUORO-4-HYDROXYQUINOLIN-2(1H)-ONE
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PubChem ID
CID: 135435181
SID: 15225363
Canonical SMILES
Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2ccc(F)cc12
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Compound Formula C21H18FN3O4S
Compound Structure
Protein Name
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
EC50 = 38 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM
2 IC50 = 13 nM
3 IC50 = 49 nM