Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-Amino-3-methyl-butyric acid (2R,3R,4R,5R)-4-bromo-4-chloro-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-[(S)-((S)-1-isopropoxycarbonyl-ethylamino)-(naphthalen-1-yloxy)-phosphoryloxymethyl]-tetrahydro-furan-3-yl ester
    Show/Hide
 PubChem ID
CID: 126618108
Canonical SMILES
CC(C)OC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@](Cl)(Br)[C@@H]1OC(=O)[C@@H](N)C(C)C)Oc1cccc2ccccc12
    Show/Hide
Compound Formula C30H37BrClN4O10P
Compound Structure
Protein Name
 Protein Info 
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 94 nM
   TI
   LI
   LO
   TS
2
EC50 = 99 nM
   TI
   LI
   LO
   TS