Brief Information of the Compound and Protein
Compound Name
ethyl 2-[[3-(1,1-dioxo-4H-1lambda6,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-(3-methylbutyl)-2-oxoquinolin-6-yl]amino]acetate
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PubChem ID
CID: 135547941
SID: 15284280
Canonical SMILES
CCOC(=O)CNc1ccc2n(CCC(C)C)c(=O)c(C3=Nc4ccccc4S(=O)(=O)N3)c(O)c2c1
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Compound Formula C25H28N4O6S
Compound Structure
Protein Name
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
EC50 = 265 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 115 nM