Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(15-fluoro-6-oxo-7,10-diazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2,4,11(16),12,14-hexaen-4-yl)-2-(4-fluorophenyl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
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 PubChem ID
CID: 117775248
Canonical SMILES
CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1cc2-c3cc4c(F)cccc4n3CCn2c(=O)c1)-c1ccc(F)cc1
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Compound Formula C33H26F2N4O5S
Compound Structure
Protein Name
 Protein Info 
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  8
1
EC50 = 0.61 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.62 nM
   TI
   LI
   LO
   TS
3
EC50 = 1.3 nM
   TI
   LI
   LO
   TS
4
EC50 = 1.5 nM
   TI
   LI
   LO
   TS
5
EC50 = 2.2 nM
   TI
   LI
   LO
   TS
6
EC50 = 6.4 nM
   TI
   LI
   LO
   TS
7
EC50 = 9.8 nM
   TI
   LI
   LO
   TS
8
EC50 = 11 nM
   TI
   LI
   LO
   TS