Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-fluorophenyl)-5-(15-fluoro-3,8,10-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(17),2(7),3,5,8,11(16),12,14-octaen-4-yl)-N-methyl-6-[methyl(methylsulfonyl)amino]-1-benzofuran-3-carboxamide
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 PubChem ID
CID: 78318214
Canonical SMILES
CNC(=O)c1c(oc2cc(N(C)S(C)(=O)=O)c(cc12)-c1ccc2ncn3c(cc4c(F)cccc34)c2n1)-c1ccc(F)cc1
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Compound Formula C32H23F2N5O4S
Compound Structure
Protein Name
 Protein Info 
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  11
1
EC50 = 0.63 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.68 nM
   TI
   LI
   LO
   TS
3
EC50 = 1 nM
   TI
   LI
   LO
   TS
4
EC50 = 1.4 nM
   TI
   LI
   LO
   TS
5
EC50 = 2 nM
   TI
   LI
   LO
   TS
6
EC50 = 2.4 nM
   TI
   LI
   LO
   TS
7
EC50 = 3.1 nM
   TI
   LI
   LO
   TS
8
EC50 = 3.2 nM
   TI
   LI
   LO
   TS
9
EC50 = 3.3 nM
   TI
   LI
   LO
   TS
10
EC50 = 3.4 nM
   TI
   LI
   LO
   TS
11
EC50 = 16 nM
   TI
   LI
   LO
   TS