Brief Information of the Compound and Protein
Compound Name
2-(4-fluorophenyl)-6-[2-hydroxyethyl(methylsulfonyl)amino]-N-methyl-5-[3-[(1-phenylcyclopropyl)carbamoyl]phenyl]-1-benzofuran-3-carboxamide
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PubChem ID
CID: 59275182
Canonical SMILES
CNC(=O)c1c(oc2cc(N(CCO)S(C)(=O)=O)c(cc12)-c1cccc(c1)C(=O)NC1(CC1)c1ccccc1)-c1ccc(F)cc1
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Compound Formula C35H32FN3O6S
Compound Structure
Protein Name
RNA-directed RNA polymerase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q8JXU8
Gene Name
NS5B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  4
1
EC50 = 5.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 6.2 nM
   TI
   LI
   LO
   TS
3
EC50 = 8.6 nM
   TI
   LI
   LO
   TS
4
EC50 = 64 nM
   TI
   LI
   LO
   TS