Protein Information

General Information of the Protein

Protein ID	PT02581
Protein Name	Cytidine deaminase
Secondarily Protein Name	Cytidine aminohydrolase
Gene Name	CDA
Secondarily Gene Name	CDD
Sequence	MAQKRPACTLKPECVQQLLVCSQEAKKSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ Show/Hide
Organism	Homo sapiens, Human
Protein Classification	Enzyme > Hydrolase
Function	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. Show/Hide
Uniprot ID	P32320
Ensembl ID	ENSG00000158825
HGNC ID	HGNC:1712

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000148 , Huh-7

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0849915 Compound Info	4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one Show/Hide	C9H12FN3O4	1
1	Km = 27000 nM Bioactivity Info	TI LI LO TS
CP0761905 Compound Info	(cytidine) 4-Amino-1-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one Show/Hide	C9H13N3O5	1
1	Km = 40000 nM Bioactivity Info	TI LI LO TS
CP0036494 Compound Info	DEOXYCYTIDINE Show/Hide	C9H13N3O4	1
1	Km = 41000 nM Bioactivity Info	TI LI LO TS
CP0378585 Compound Info	2''-C-Mecytosine Show/Hide	C10H15N3O5	1
1	Km = 3100000 nM Bioactivity Info	TI LI LO TS
CP0354650 Compound Info	4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one Show/Hide	C10H14FN3O4	1
1	Km = 4000000 nM Bioactivity Info	TI LI LO TS

Clinical Information about the Protein

Target 1 ( Cytidine deaminase (CDA) )