Brief Information of the Cell Line and Protein
Cell Line ID: CL000148 , Huh-7
Synonyms
HuH-7
HUH-7
HuH7
Huh7
HUH7
HUH7.0
JTC-39
Japanese Tissue Culture-39
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0336
Protein ID: PT01172 , Progesterone receptor
Gene Name PGR
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P06401
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000148  Protein ID: PT01172
 
Compound ID Compound Name Compound Formula
CP0805098
Methyl 4-(2-Chlorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-propylpyridine-3-carboxylate
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C18H19ClN2O2
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0906869
Methyl 2-Butyl-4-(2-chlorophenyl)-5-cyano-1,4-dihydro-6-methylpyridine-3-carboxylate
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C19H21ClN2O2
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0683120
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,4-dihydro-2,6-dimethylpyridine-3-carboxylate
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C16H14ClFN2O2
 1
1
IC50 = 900 nM
   TI
   LI
   LO
   TS
CP0675470
Methyl 2-((1H-Pyrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
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C19H16ClFN4O2
 1
1
IC50 = 5500 nM
   TI
   LI
   LO
   TS
CP0645727
Methyl 2-((1H-1,2,4-Triazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
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C18H15ClFN5O2
 1
1
IC50 = 7000 nM
   TI
   LI
   LO
   TS
CP0645863
(R)-Methyl 2-((1H-Tetrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
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C17H14ClFN6O2
 1
1
IC50 = 7200 nM
   TI
   LI
   LO
   TS
CP0675469
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-6-methyl-2-(trifluoromethyl)-1,4-dihydropyridine-3-carboxylate
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C16H11ClF4N2O2
 1
1
IC50 = 7800 nM
   TI
   LI
   LO
   TS
CP0645725
Methyl 2-((1H-Imidazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
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C19H16ClFN4O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0790986
Methyl 2-((1H-Tetrazol-1-yl)methyl)-4-(2-chloro-4-fluorophenyl)-5-cyano-6-methyl-1,4-dihydropyridine-3-carboxylate
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C17H14ClFN6O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0858705
Methyl 4-(2-Chloro-4-fluorophenyl)-5-cyano-1,4-dihydro-6-methyl-2-propylpyridine-3-carboxylate
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C18H18ClFN2O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS