Brief Information of the Cell Line and Protein
Cell Line ID: CL000148 , Huh-7
Synonyms
HuH-7
HUH-7
HuH7
Huh7
HUH7
HUH7.0
JTC-39
Japanese Tissue Culture-39
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0336
Protein ID: PT06441 , Scavenger receptor class B member 1
Gene Name SCARB1
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q8WTV0
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000148  Protein ID: PT06441
 
Compound ID Compound Name Compound Formula
CP0259227
5-[9-[3-(3,5-difluorophenyl)sulfanylpropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
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C24H23F2N3OS
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0389671
5-[9-[3-(6-fluoro-1H-benzimidazol-2-yl)propyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
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C25H24FN5O
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0470424
2-[9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-1,3-oxazole
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C24H26N4O2
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0477003
5-[9-[3-(3,4-difluorophenoxy)propyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
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C24H23F2N3O2
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0477004
5-[9-[3-(3,5-difluorophenoxy)propyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
   Show/Hide
C24H23F2N3O2
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0497406
5-[9-[3-(3,4-difluorophenyl)sulfanylpropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
   Show/Hide
C24H23F2N3OS
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0497407
5-[9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
   Show/Hide
C26H31N5O2
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0534135
N,N-dimethyl-3-[6-(3-methyl-1,2,4-oxadiazol-5-yl)-1,2,3,4-tetrahydrocarbazol-9-yl]propane-1-sulfonamide
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C20H26N4O3S
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0534139
9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-nitro-1,2,3,4-tetrahydrocarbazole
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C23H28N4O3
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0534140
methyl 9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazole-3-carboxylate
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C23H27N3O3
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0535743
9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-(3-methyl-1,2,4-oxadiazol-5-yl)-2,3-dihydro-1H-carbazol-4-one
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C26H29N5O3
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0535744
5-[9-[3-(3,5-difluorophenoxy)-2-fluoropropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
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C24H22F3N3O2
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0542313
9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-(tetrazol-1-yl)-1,2,3,4-tetrahydrocarbazole
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C24H29N7O
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0542314
3-methyl-5-[9-[3-[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-1,2,4-oxadiazole
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C24H24F3N5O2
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0571451
5-[9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
   Show/Hide
C24H27N5O2
 1
1
IC50 = 1.5 nM
   TI
   LI
   LO
   TS
CP0414259
5-[9-[3-(3,5-difluorophenyl)sulfonylpropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
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C24H23F2N3O3S
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0477002
9-[3-(3,5-difluorophenyl)sulfanylpropyl]-6-(3-methyl-1,2,4-oxadiazol-5-yl)-2,3-dihydro-1H-carbazol-4-one
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C24H21F2N3O2S
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0535746
3-[9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-5-methyl-1,2,4-oxadiazole
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C26H31N5O2
 1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
CP0571848
4,6-dimethoxy-N-[3-(6-methylsulfonyl-1,2,3,4-tetrahydrocarbazol-9-yl)propyl]pyrimidin-2-amine
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C22H28N4O4S
 1
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
CP0414258
5-[9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6,6-difluoro-7,8-dihydro-5H-carbazol-3-yl]-3-methyl-1,2,4-oxadiazole
   Show/Hide
C26H29F2N5O2
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0477005
9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-(4-propyltriazol-1-yl)-1,2,3,4-tetrahydrocarbazole
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C28H36N6O
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0523695
5-[9-[3-(3,5-difluorophenyl)sulfinylpropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
   Show/Hide
C24H23F2N3O2S
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0534136
2-[9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-5-methyl-1,3,4-oxadiazole
   Show/Hide
C26H31N5O2
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0534138
9-[3-[(4,6-dimethoxypyrimidin-2-yl)amino]propyl]-5,6,7,8-tetrahydrocarbazole-3-carbonitrile
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C22H25N5O2
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0543304
9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazole-3-carbonitrile
   Show/Hide
C22H24N4O
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0571847
5-[9-[3-(3,5-difluorophenyl)sulfanylpropyl]-6,6-difluoro-7,8-dihydro-5H-carbazol-3-yl]-3-methyl-1,2,4-oxadiazole
   Show/Hide
C24H21F4N3OS
 1
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
CP0470425
9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-methylsulfonyl-1,2,3,4-tetrahydrocarbazole
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C24H31N3O3S
 1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CP0389673
3-(6-cyano-1,2,3,4-tetrahydrocarbazol-9-yl)-N,N-dimethylpropane-1-sulfonamide
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C18H23N3O2S
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0534137
9-[3-(1H-benzimidazol-2-yl)propyl]-5,6,7,8-tetrahydrocarbazole-3-carbonitrile
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C23H22N4
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0535745
2-[9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-4,5-dihydro-1,3-oxazole
   Show/Hide
C24H28N4O2
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0535747
9-[3-(1H-benzimidazol-2-yl)propyl]-6-methylsulfonyl-1,2,3,4-tetrahydrocarbazole
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C23H25N3O2S
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0543303
9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-[4-(fluoromethyl)triazol-1-yl]-1,2,3,4-tetrahydrocarbazole
   Show/Hide
C26H31FN6O
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0570526
9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-6-methylsulfonyl-1,2,3,4-tetrahydrocarbazole
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C22H27N3O3S
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0542315
N,N-dimethyl-3-(6-methylsulfonyl-1,2,3,4-tetrahydrocarbazol-9-yl)propane-1-sulfonamide
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C18H26N2O4S2
 1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS