General Information of the Compound
Compound ID
CP0571451
Compound Name
5-[9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
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Structure
Formula
C24H27N5O2
Molecular Weight
417.513
Canonical SMILES
Cc1noc(n1)-c1ccc2n(CCCOc3nc(C)cc(C)n3)c3CCCCc3c2c1
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InChI
InChI=1S/C24H27N5O2/c1-15-13-16(2)26-24(25-15)30-12-6-11-29-21-8-5-4-7-19(21)20-14-18(9-10-22(20)29)23-27-17(3)28-31-23/h9-10,13-14H,4-8,11-12H2,1-3H3
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InChIKey
IIBHCNVPYWOTGX-UHFFFAOYSA-N
Physicochemical Property
logP
4.75446
Rotatable Bonds
6
Heavy Atom Count
31
Polar Areas
78.86
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 62707568
SID: 148139237
ChEMBL ID
CHEMBL2179499
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06441, Scavenger receptor class B member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7 Homo sapiens (Human)  1
1
IC50 = 1.5 nM
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