| Compound ID |
Compound Name |
Compound Formula |
|
CP0492055
|
1-benzyl-3-(3-nitrophenyl)quinoxalin-2-one
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|
C21H15N3O3
|
2
|
| 1 |
EC50 = 9 nM
|
|
|
| 2 |
EC50 = 21 nM
|
|
|
|
CP0378745
|
3-(3-nitrophenyl)-1-(thiophen-2-ylmethyl)quinoxalin-2-one
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|
C19H13N3O3S
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
EC50 = 70 nM
|
|
|
|
CP0911368
|
(R)-(6-Fluoro-3,9-dimethyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]-indol-2-yl)-(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
Show/Hide
|
C18H16F4N4O
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0560395
|
3-(2,1,3-benzoxadiazol-5-yl)-1-benzylquinoxalin-2-one
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|
C21H14N4O2
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0532736
|
3-Amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid ((S)-3,3,3-trifluoro-2-hydroxy-2-methyl-propyl)-amide
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|
C11H10BrF6N3O2
|
3
|
| 1 |
EC50 = 18 nM
|
|
|
| 2 |
EC50 = 43 nM
|
|
|
| 3 |
EC50 = 150 nM
|
|
|
|
CP0492083
|
1-(furan-2-ylmethyl)-3-(3-nitrophenyl)quinoxalin-2-one
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|
C19H13N3O4
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0957615
|
(+/-)-(6-Fluoro-3,9-dimethyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]-indol-2-yl)-(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
Show/Hide
|
C18H16F4N4O
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0510979
|
4-N-(1,3-benzothiazol-6-yl)-2-N,2-N-diethyl-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C17H16F6N6OS
|
2
|
| 1 |
EC50 = 30 nM
|
|
|
| 2 |
EC50 = 50 nM
|
|
|
|
CP0920761
|
(+/-)-(6-Fluoro-1,9-dimethyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]-indol-2-yl)-(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
Show/Hide
|
C18H16F4N4O
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0429064
|
4-N-methyl-2-N-phenyl-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine
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|
C13H13F4N5O
|
2
|
| 1 |
EC50 = 31 nM
|
|
|
| 2 |
EC50 = 40 nM
|
|
|
|
CP0088272
|
CHEBI:66901
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|
C24H28N2O3
|
3
|
| 1 |
EC50 = 49 nM
|
|
|
| 2 |
EC50 = 70 nM
|
|
|
| 3 |
EC50 = 131 nM
|
|
|
|
CP0961946
|
(S/R)-(6-Fluoro-1,9-dimethyl-1,3,4,5-tetrahydro-2H-pyrido-[4,3-b]indol-2-yl)-(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
Show/Hide
|
C18H16F4N4O
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0548756
|
3-(3-nitrophenyl)-1-(pyridin-2-ylmethyl)quinoxalin-2-one
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|
C20H14N4O3
|
1
|
| 1 |
EC50 = 52 nM
|
|
|
|
CP0561680
|
3-(3-nitrophenyl)-1-prop-2-enylquinoxalin-2-one
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|
C17H13N3O3
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0546145
|
(6-fluoro-9-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H14F4N4O
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0497902
|
1-benzyl-6-bromo-3-(3-nitrophenyl)quinoxalin-2-one
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|
C21H14BrN3O3
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0492082
|
1-ethyl-3-(3-nitrophenyl)quinoxalin-2-one
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|
C16H13N3O3
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0476428
|
1-benzyl-6-chloro-3-(3-nitrophenyl)quinoxalin-2-one
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|
C21H14ClN3O3
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0551217
|
US10117858, Example 5
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|
C12H13F6N3O3
|
3
|
| 1 |
EC50 = 79 nM
|
|
|
| 2 |
EC50 = 113 nM
|
|
|
| 3 |
EC50 = 497 nM
|
|
|
|
CP0943934
|
(R/S)-(6-Fluoro-1,9-dimethyl-1,3,4,5-tetrahydro-2H-pyrido-[4,3-b]indol-2-yl)-(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
Show/Hide
|
C18H16F4N4O
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0564126
|
(6-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C16H12F4N4O
|
1
|
| 1 |
EC50 = 96 nM
|
|
|
|
CP0548755
|
1-benzyl-5-chloro-3-(3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C21H14ClN3O3
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0478967
|
6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-4-N-methyl-2-N-phenyl-1,3,5-triazine-2,4-diamine
Show/Hide
|
C13H11F6N5O
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0426404
|
[6-(dimethylamino)-1H-indol-2-yl]-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone
Show/Hide
|
C22H22N4O
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0507526
|
(6-fluoro-8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H14F4N4O2
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0420995
|
N-[5-[2-(5-chloro-2-methoxyanilino)-5-(4-phenyltriazol-1-yl)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C27H26ClN7O2S2
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0447468
|
2-N,2-N-diethyl-4-N-(3-fluorophenyl)-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H16F7N5O
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0565135
|
4-N-(1,3-benzoxazol-6-yl)-2-N,2-N-diethyl-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C17H16F6N6O2
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0422937
|
(6,8-difluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C16H11F5N4O
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0560775
|
[6-(dimethylamino)-1H-indol-2-yl]-(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0564124
|
(6,9-difluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C16H11F5N4O
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0447469
|
3-[[4-(diethylamino)-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-1,3,5-triazin-2-yl]amino]benzoic acid
Show/Hide
|
C17H17F6N5O3
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0426408
|
[8-(trifluoromethoxy)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H12F6N4O2
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0562816
|
3-(3-nitrophenyl)-1-propylquinoxalin-2-one
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|
C17H15N3O3
|
1
|
| 1 |
EC50 = 177 nM
|
|
|
|
CP0534898
|
methyl 2-amino-5-(furan-2-yl)-4-(trifluoromethyl)benzoate
Show/Hide
|
C13H10F3NO3
|
2
|
| 1 |
EC50 = 180 nM
|
|
|
| 2 |
EC50 = 30000 nM
|
|
|
|
CP0077077
|
N,N-dimethyl-2-[4-[2-pyridin-2-yl-6-(thiophen-3-ylmethyl)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]ethanamine
Show/Hide
|
C25H33N7S
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0148607
|
N-(3-imidazol-1-ylpropyl)-6-[(4-methoxyphenyl)methyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-amine
Show/Hide
|
C26H29N7O
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0403559
|
N-[2-[[6-[(4-fluorophenyl)methyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]amino]ethyl]acetamide
Show/Hide
|
C23H25FN6O
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0409074
|
6-[(4-fluorophenyl)methyl]-2-pyridin-2-yl-N-(2-pyrrolidin-1-ylethyl)-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-amine
Show/Hide
|
C25H29FN6
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0575432
|
2-N,2-N-diethyl-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-4-N-(3-nitrophenyl)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H16F6N6O3
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0441162
|
3-(2-amino-5-nitrophenyl)-1-benzylquinoxalin-2-one
Show/Hide
|
C21H16N4O3
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0486138
|
(7-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H15F3N4O
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0426407
|
1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C16H13F3N4O
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0555910
|
(6-fluoro-8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H14F4N4O
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0493359
|
2-N,2-N-diethyl-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-4-N-phenyl-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H17F6N5O
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0944923
|
2-(2-(1H-indol-3-yl)-N-methylacetamido)-N-(4-isopropylphenyl)-2-phenylacetamide
Show/Hide
|
C28H29N3O2
|
2
|
| 1 |
EC50 = 260 nM
|
|
|
| 2 |
EC50 = 990 nM
|
|
|
|
CP0507525
|
(8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H15F3N4O
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0144592
|
N-[12-(5-chloro-2-methoxyanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-2,2-dimethylpropanamide
Show/Hide
|
C21H23ClN4O2S2
|
2
|
| 1 |
EC50 = 300 nM
|
|
|
| 2 |
IC50 = 2300 nM
|
|
|
|
CP0366026
|
N,N-dimethyl-2-[4-[6-[(4-propan-2-ylphenyl)methyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]ethanamine
Show/Hide
|
C30H41N7
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0429595
|
N-ethyl-N-[1-[6-[(4-methoxyphenyl)methyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]pyrrolidin-3-yl]acetamide
Show/Hide
|
C28H34N6O2
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0544202
|
1-benzyl-3-(3-bromophenyl)quinoxalin-2-one
Show/Hide
|
C21H15BrN2O
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0426403
|
(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H15F3N4O2
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
|
CP0455463
|
2-[4-[6-[(4-methoxyphenyl)methyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]ethanol
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
EC50 = 400 nM
|
|
|
|
CP0546144
|
[5-(trifluoromethyl)-1H-pyrazol-3-yl]-[8-(trifluoromethyl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]methanone
Show/Hide
|
C17H12F6N4O
|
1
|
| 1 |
EC50 = 440 nM
|
|
|
|
CP0486136
|
(9-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H15F3N4O
|
1
|
| 1 |
EC50 = 480 nM
|
|
|
|
CP0546143
|
(8-fluoro-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C16H12F4N4O
|
1
|
| 1 |
EC50 = 480 nM
|
|
|
|
CP0567308
|
3-[[4-(diethylamino)-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazin-2-yl]amino]benzoic acid
Show/Hide
|
C17H19F4N5O3
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0871863
|
(4-Fluoro-1-methyl-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indol-11-yl)(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
Show/Hide
|
C19H16F4N4O
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0544203
|
methyl 4-amino-3-(4-benzyl-3-oxoquinoxalin-2-yl)benzoate
Show/Hide
|
C23H19N3O3
|
1
|
| 1 |
EC50 = 550 nM
|
|
|
|
CP0533407
|
[6-fluoro-8-(trifluoromethyl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H11F7N4O
|
1
|
| 1 |
EC50 = 570 nM
|
|
|
|
CP0441163
|
1-benzyl-3-(4-fluoro-3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C21H14FN3O3
|
1
|
| 1 |
EC50 = 690 nM
|
|
|
|
CP0127853
|
MLS000561583
Show/Hide
|
C19H21ClN4O2S2
|
2
|
| 1 |
EC50 = 700 nM
|
|
|
| 2 |
Kd = 700 nM
|
|
|
|
CP0223510
|
N-[1-[6-[(4-chlorophenyl)methyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]piperidin-4-yl]acetamide
Show/Hide
|
C26H29ClN6O
|
1
|
| 1 |
EC50 = 700 nM
|
|
|
|
CP0566536
|
2-N,2-N-diethyl-4-N-(4-fluorophenyl)-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H16F7N5O
|
1
|
| 1 |
EC50 = 700 nM
|
|
|
|
CP0479966
|
N,1-dibenzyl-5-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]pyrazole-3-carboxamide
Show/Hide
|
C27H29N5O2S
|
1
|
| 1 |
EC50 = 750 nM
|
|
|
|
CP0499700
|
1-benzyl-7-chloro-3-(3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C21H14ClN3O3
|
1
|
| 1 |
EC50 = 760 nM
|
|
|
|
CP0546367
|
N-[4-nitro-2-(12-oxo-4-oxa-1,10-diazatricyclo[7.3.1.05,13]trideca-5,7,9(13),10-tetraen-11-yl)phenyl]acetamide
Show/Hide
|
C18H14N4O5
|
1
|
| 1 |
EC50 = 820 nM
|
|
|
|
CP0564121
|
(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-(3-phenyl-1H-pyrazol-5-yl)methanone
Show/Hide
|
C22H20N4O2
|
1
|
| 1 |
EC50 = 820 nM
|
|
|
|
CP0326300
|
2-[4-[6-(cyclohexylmethyl)-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]-N,N-dimethylethanamine
Show/Hide
|
C27H41N7
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
|
CP0510978
|
4-[[4-(diethylamino)-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-1,3,5-triazin-2-yl]amino]benzoic acid
Show/Hide
|
C17H17F6N5O3
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
|
CP0575433
|
2-N,2-N-diethyl-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-4-N-(1H-indazol-6-yl)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C17H17F6N7O
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
|
CP0497131
|
5-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-N-(4-methoxyphenyl)-1-prop-2-enylpyrazole-3-carboxamide
Show/Hide
|
C23H27N5O3S
|
1
|
| 1 |
EC50 = 930 nM
|
|
|
|
CP0466271
|
(9-fluoro-6-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H14F4N4O
|
1
|
| 1 |
EC50 = 940 nM
|
|
|
|
CP0494098
|
1-[(5-chloro-2-methoxyphenyl)methyl]-5-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-N-(4-methoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C28H30ClN5O4S
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0504264
|
N-[5-[2-[(5-chloro-2-methoxyphenyl)methyl]-5-(morpholine-4-carbonyl)pyrazol-3-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C25H30ClN5O4S
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0378746
|
1-benzyl-3-(4-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C21H15N3O3
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0492056
|
1-benzyl-3-(2-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C21H15N3O3
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0567093
|
3-(4-benzyl-3-oxoquinoxalin-2-yl)benzonitrile
Show/Hide
|
C22H15N3O
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0575500
|
1-benzyl-3-[4-(trifluoromethyl)phenyl]quinoxalin-2-one
Show/Hide
|
C22H15F3N2O
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0047295
|
N-[5-[2-(5-chloro-2-methoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C21H17ClN4O2S2
|
3
|
| 1 |
EC50 = 1100 nM
|
|
|
| 2 |
IC50 = 6000 nM
|
|
|
| 3 |
Kd = 900 nM
|
|
|
|
CP0911367
|
(S)-(6-Fluoro-3,9-dimethyl-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]-indol-2-yl)-(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
Show/Hide
|
C18H16F4N4O
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0546142
|
(6-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H15F3N4O
|
1
|
| 1 |
EC50 = 1140 nM
|
|
|
|
CP0476844
|
2-N,2-N-diethyl-4-N-(3-nitrophenyl)-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H18F4N6O3
|
1
|
| 1 |
EC50 = 1200 nM
|
|
|
|
CP0912018
|
(+/-)-(4-Fluoro-1-methyl-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indol-11-yl)-(5-(trifluoromethyl)-1H-pyrazol-3-yl)methanone
Show/Hide
|
C19H16F4N4O
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0305495
|
1-(6-benzyl-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C25H28N6O
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0565405
|
(8-propan-2-yl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C19H19F3N4O
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0481721
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]-3,4-dimethoxybenzamide
Show/Hide
|
C23H24N4O3
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0432461
|
N-[5-[2-amino-5-(4-phenyltriazol-1-yl)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C20H21N7OS2
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0148604
|
2-[4-(6-benzyl-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl)piperazin-1-yl]-N,N-dimethylethanamine
Show/Hide
|
C27H35N7
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0497612
|
N-[5-[2-(5-chloro-2-methoxyanilino)-5-[4-(hydroxymethyl)triazol-1-yl]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Show/Hide
|
C22H24ClN7O3S2
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0548550
|
2-N,2-N-diethyl-4-N-(3-fluorophenyl)-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H18F5N5O
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0466270
|
2-[5-(trifluoromethyl)-1H-pyrazole-3-carbonyl]-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-carbonitrile
Show/Hide
|
C17H12F3N5O
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0466274
|
(6-fluoro-3,3,9-trimethyl-4,5-dihydro-1H-pyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C19H18F4N4O
|
1
|
| 1 |
EC50 = 1910 nM
|
|
|
|
CP0406732
|
2-N,2-N-diethyl-4-N-phenyl-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H19F4N5O
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
|
CP0426406
|
(8-methoxy-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C18H17F3N4O2
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0352404
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]-3-methoxybenzamide
Show/Hide
|
C22H22N4O2
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0313065
|
4-cyclohexyloxy-2-[1-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]ethyl]quinazoline
Show/Hide
|
C27H34N4O4S
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0230834
|
2-[4-[6-[(4-methoxyphenyl)methyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]piperazin-1-yl]acetamide
Show/Hide
|
C26H31N7O2
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0486139
|
(7-fluoro-10-methyl-2,4,5,6-tetrahydro-1H-azepino[4,5-b]indol-3-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C18H16F4N4O
|
1
|
| 1 |
EC50 = 2300 nM
|
|
|
|
CP0566535
|
4-[[4-(diethylamino)-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazin-2-yl]amino]benzoic acid
Show/Hide
|
C17H19F4N5O3
|
1
|
| 1 |
EC50 = 2500 nM
|
|
|
|
CP0148603
|
Lumacaftor
Show/Hide
|
C24H18F2N2O5
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0409213
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]pyridine-3-carboxamide
Show/Hide
|
C20H19N5O
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0526233
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]-5-methoxypyridine-2-carboxamide
Show/Hide
|
C21H21N5O2
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0061241
|
1-(6-benzyl-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl)piperidin-3-ol
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0066401
|
2-[4-(6-benzyl-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl)piperazin-1-yl]acetamide
Show/Hide
|
C25H29N7O
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0493360
|
4-N-(3-chlorophenyl)-2-N,2-N-diethyl-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H16ClF6N5O
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0567309
|
2-N,2-N-diethyl-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-4-N-(1H-indazol-5-yl)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C17H17F6N7O
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0548186
|
(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[2-(trifluoromethyl)-1H-imidazol-5-yl]methanone
Show/Hide
|
C17H15F3N4O2
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0501923
|
1-[(5-chloro-2-methoxyphenyl)methyl]-5-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-N-(2-hydroxyethyl)pyrazole-3-carboxamide
Show/Hide
|
C23H28ClN5O4S
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0514944
|
N-benzyl-5-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1-prop-2-enylpyrazole-3-carboxamide
Show/Hide
|
C23H27N5O2S
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0410350
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]-4-methoxybenzamide
Show/Hide
|
C22H22N4O2
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0464388
|
N-[3-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]propyl]pyridine-3-carboxamide
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0363208
|
6-benzyl-N-[3-(4-methylpiperazin-1-yl)propyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-amine
Show/Hide
|
C27H35N7
|
1
|
| 1 |
EC50 = 3100 nM
|
|
|
|
CP0494097
|
1-(4-bromophenyl)-5-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-N-(4-methoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C26H26BrN5O3S
|
1
|
| 1 |
EC50 = 3400 nM
|
|
|
|
CP0077076
|
1-[6-[(4-methoxyphenyl)methyl]-2-pyridin-2-yl-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]piperidine-4-carboxamide
Show/Hide
|
C26H30N6O2
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0409211
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]-2,6-dimethoxybenzamide
Show/Hide
|
C23H24N4O3
|
1
|
| 1 |
EC50 = 3700 nM
|
|
|
|
CP0555924
|
(5-bromofuran-2-yl)-(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone
Show/Hide
|
C17H15BrN2O3
|
1
|
| 1 |
EC50 = 3700 nM
|
|
|
|
CP0466268
|
(1-phenylpyrazol-4-yl)-(1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)methanone
Show/Hide
|
C21H18N4O
|
1
|
| 1 |
EC50 = 4100 nM
|
|
|
|
CP0522494
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]-2,4-dimethoxybenzamide
Show/Hide
|
C23H24N4O3
|
1
|
| 1 |
EC50 = 4200 nM
|
|
|
|
CP0400692
|
N-[3-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]propyl]-4-methoxybenzamide
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
EC50 = 4300 nM
|
|
|
|
CP0562817
|
1-(naphthalen-2-ylmethyl)-3-(3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C25H17N3O3
|
1
|
| 1 |
EC50 = 4300 nM
|
|
|
|
CP0434920
|
N-[3-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]propyl]-3-methoxybenzamide
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
EC50 = 4600 nM
|
|
|
|
CP0506352
|
methyl 1-[2-(5-chloro-2-methoxyanilino)-4-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-1,3-thiazol-5-yl]triazole-4-carboxylate
Show/Hide
|
C23H24ClN7O4S2
|
1
|
| 1 |
EC50 = 4600 nM
|
|
|
|
CP0466674
|
2-N,2-N-diethyl-4-N-(4-fluorophenyl)-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H18F5N5O
|
1
|
| 1 |
EC50 = 4800 nM
|
|
|
|
CP0432462
|
2,2-dimethyl-N-[4-methyl-5-[2-(methylamino)-5-(4-phenyltriazol-1-yl)-1,3-thiazol-4-yl]-1,3-thiazol-2-yl]propanamide
Show/Hide
|
C21H23N7OS2
|
1
|
| 1 |
EC50 = 4900 nM
|
|
|
|
CP0566929
|
1-benzyl-3-phenylquinoxalin-2-one
Show/Hide
|
C21H16N2O
|
1
|
| 1 |
EC50 = 5000 nM
|
|
|
|
CP0457974
|
4-N-(3-chlorophenyl)-2-N,2-N-diethyl-6-(2,2,3,3-tetrafluoropropoxy)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C16H18ClF4N5O
|
1
|
| 1 |
EC50 = 5400 nM
|
|
|
|
CP0507528
|
(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-(5-propan-2-yl-1H-pyrazol-3-yl)methanone
Show/Hide
|
C19H22N4O2
|
1
|
| 1 |
EC50 = 5700 nM
|
|
|
|
CP0012708
|
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
Show/Hide
|
C15H10O5
|
2
|
| 1 |
EC50 = 6170 nM
|
|
|
| 2 |
EC50 = 14200 nM
|
|
|
|
CP0489618
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]pyrazine-2-carboxamide
Show/Hide
|
C19H18N6O
|
1
|
| 1 |
EC50 = 6700 nM
|
|
|
|
CP0507524
|
(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methanone
Show/Hide
|
C18H17F3N4O2
|
1
|
| 1 |
EC50 = 7100 nM
|
|
|
|
CP0489617
|
N-[2-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]ethyl]pyridine-4-carboxamide
Show/Hide
|
C20H19N5O
|
1
|
| 1 |
EC50 = 7300 nM
|
|
|
|
CP0522495
|
N-[3-[(3-cyano-5,7-dimethylquinolin-2-yl)amino]propyl]pyridine-4-carboxamide
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
EC50 = 8200 nM
|
|
|
|
CP0453896
|
ethyl 2-benzyl-5-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]pyrazole-3-carboxylate
Show/Hide
|
C22H26N4O3S
|
1
|
| 1 |
EC50 = 8500 nM
|
|
|
|
CP0547834
|
methyl 3-(4-benzyl-3-oxoquinoxalin-2-yl)-4-nitrobenzoate
Show/Hide
|
C23H17N3O5
|
1
|
| 1 |
EC50 = 9900 nM
|
|
|
|
CP0411358
|
4-amino-3-(4-benzyl-3-oxoquinoxalin-2-yl)benzoic acid
Show/Hide
|
C22H17N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0436446
|
1-benzyl-6,7-dimethyl-3-(3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C23H19N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0476429
|
5-benzyl-9-nitro-2-(trifluoromethyl)indolo[2,3-b]quinoxaline
Show/Hide
|
C22H13F3N4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0492080
|
1-benzyl-8-methyl-3-(3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C22H17N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0492081
|
1-methyl-3-(3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C15H11N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0497901
|
1-benzyl-6,7-dichloro-3-(3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C21H13Cl2N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0497903
|
3-(3-nitrophenyl)-1H-quinoxalin-2-one
Show/Hide
|
C14H9N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0543168
|
11-(2-amino-5-nitrophenyl)-2-phenyl-4-oxa-1,10-diazatricyclo[7.3.1.05,13]trideca-5,7,9(13),10-tetraen-12-one
Show/Hide
|
C22H16N4O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0564172
|
5-benzyl-9-fluoro-2-(trifluoromethyl)indolo[2,3-b]quinoxaline
Show/Hide
|
C22H13F4N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0564730
|
3-(4-benzyl-3-oxoquinoxalin-2-yl)-4-nitrobenzoic acid
Show/Hide
|
C22H15N3O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0573845
|
1-benzyl-6,7-difluoro-3-(3-nitrophenyl)quinoxalin-2-one
Show/Hide
|
C21H13F2N3O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0466272
|
(8-methylsulfonyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[5-(trifluoromethyl)-1H-pyrazol-3-yl]methanone
Show/Hide
|
C17H15F3N4O3S
|
1
|
| 1 |
EC50 = 10500 nM
|
|
|
|
CP0466269
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(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-(1H-pyrazol-5-yl)methanone
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C16H16N4O2
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1
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| 1 |
EC50 = 10600 nM
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CP0323275
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MLS001204421
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C22H22N4O2
|
1
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| 1 |
EC50 = 11000 nM
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CP0510976
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2-N,2-N-diethyl-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-4-N-(4-nitrophenyl)-1,3,5-triazine-2,4-diamine
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C16H16F6N6O3
|
1
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| 1 |
EC50 = 18000 nM
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CP0507527
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(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-(5-methyl-1H-pyrazol-3-yl)methanone
Show/Hide
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C17H18N4O2
|
1
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| 1 |
EC50 = 60000 nM
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CP0474732
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9-(5-bromofuran-2-yl)-12,14-dimethyl-13,15-dioxo-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylic acid
Show/Hide
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C26H18BrN3O6
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2
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| 1 |
IC50 = 8 nM
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| 2 |
IC50 = 40 nM
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CP0494269
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9-(5-bromofuran-2-yl)-12,14-dimethyl-4-nitro-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-13,15-dione
Show/Hide
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C25H17BrN4O6
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2
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| 1 |
IC50 = 25 nM
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|
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| 2 |
IC50 = 120 nM
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CP0503352
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12,14-dimethyl-9-(5-methylfuran-2-yl)-4-nitro-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-13,15-dione
Show/Hide
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C26H20N4O6
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2
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| 1 |
IC50 = 25 nM
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| 2 |
IC50 = 100 nM
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CP0524634
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ethyl 9-(5-bromofuran-2-yl)-12,14-dimethyl-13,15-dioxo-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylate
Show/Hide
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C28H22BrN3O6
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2
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| 1 |
IC50 = 25 nM
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| 2 |
IC50 = 50 nM
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CP0501628
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9-(5-bromofuran-2-yl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C25H19BrN4O3
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2
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| 1 |
IC50 = 50 nM
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| 2 |
IC50 = 90 nM
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CP0527319
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ethyl 12,14-dimethyl-9-(5-methylfuran-2-yl)-13,15-dioxo-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylate
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C29H25N3O6
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1
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| 1 |
IC50 = 80 nM
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CP0385469
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7,9-Dimethyl-6-(5-methyl-furan-2-yl)-11-phenyl-6,7-dihydro-5H-5,7,9,11a-tetraaza-benzo[a]fluorene-8,10-dione
Show/Hide
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C26H22N4O3
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4
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| 1 |
IC50 = 90 nM
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|
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| 2 |
IC50 = 100 nM
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| 3 |
IC50 = 250 nM
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| 4 |
IC50 = 800 nM
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CP0471236
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9-(5-bromofuran-2-yl)-12,14-dimethyl-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C25H18BrN3O4
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2
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| 1 |
IC50 = 90 nM
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|
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| 2 |
IC50 = 200 nM
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CP0474731
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9-(5-iodofuran-2-yl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C25H19IN4O3
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2
|
| 1 |
IC50 = 100 nM
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|
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| 2 |
IC50 = 170 nM
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CP0449308
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9-(5-chlorofuran-2-yl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C25H19ClN4O3
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1
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| 1 |
IC50 = 150 nM
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|
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CP0530535
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12,14-dimethyl-9-(5-methylfuran-2-yl)-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C26H21N3O4
|
1
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| 1 |
IC50 = 150 nM
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|
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CP0388825
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9-(5-bromofuran-2-yl)-12,14-dimethyl-4-nitro-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-13,15-dione
Show/Hide
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C25H18BrN5O5
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1
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| 1 |
IC50 = 170 nM
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|
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CP0471235
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4-chloro-12,14-dimethyl-9-(5-methylfuran-2-yl)-5-nitro-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C26H19ClN4O6
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1
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| 1 |
IC50 = 170 nM
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|
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CP0435933
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9-(5-ethylfuran-2-yl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C27H24N4O3
|
1
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| 1 |
IC50 = 300 nM
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|
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CP0449301
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12,14-dimethyl-17-phenyl-9-[5-(trifluoromethyl)furan-2-yl]-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C26H19F3N4O3
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1
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| 1 |
IC50 = 350 nM
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|
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CP0425970
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9-(5-chlorofuran-2-yl)-12,14-dimethyl-17-(3-methylphenyl)-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C26H20ClN3O4
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1
|
| 1 |
IC50 = 370 nM
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|
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CP0071868
|
4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
|
C18H10F3NO3S2
|
1
|
| 1 |
IC50 = 380 nM
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|
|
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CP0503282
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9-(5-iodofuran-2-yl)-12,14-dimethyl-17-phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C25H18IN3O4
|
1
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| 1 |
IC50 = 500 nM
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|
|
|
CP0498767
|
12,14-dimethyl-9-(5-methylfuran-2-yl)-17-(3-methylphenyl)-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H23N3O4
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0500088
|
12,14-dimethyl-9-(5-methylfuran-2-yl)-17-(3-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H24N4O3
|
1
|
| 1 |
IC50 = 700 nM
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|
|
|
CP0878306
|
5-[[4-(2H-Tetrazol-5-yl)phenyl]methylene]-2-thioxo-3-[3-(trifluoromethyl)phenyl]-4-thiazolidinone
Show/Hide
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C18H10F3N5OS2
|
1
|
| 1 |
IC50 = 760 nM
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|
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CP0128193
|
4,5,12,14-tetramethyl-9-(5-methylfuran-2-yl)-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-13,15-dione
Show/Hide
|
C28H26N4O3
|
1
|
| 1 |
IC50 = 800 nM
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|
|
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CP0502575
|
12,14-dimethyl-9-(5-methylfuran-2-yl)-17-(2-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H24N4O3
|
1
|
| 1 |
IC50 = 800 nM
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|
|
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CP0569038
|
N-[13-(2-methoxy-5-nitroanilino)-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]-2,2-dimethylpropanamide
Show/Hide
|
C22H25N5O4S2
|
1
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| 1 |
IC50 = 900 nM
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|
|
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CP0478796
|
8,12,14-trimethyl-9-(5-methylfuran-2-yl)-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H24N4O3
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
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CP0100529
|
12,14-dimethyl-9-(3-nitrophenyl)-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H21N5O4
|
1
|
| 1 |
IC50 = 1200 nM
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|
|
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CP0479241
|
9-(2,3-difluorophenyl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H20F2N4O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
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CP0399202
|
2-hydroxy-5-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
|
C18H10F3NO4S2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
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CP0532249
|
4-[[3-[3-(trifluoromethyl)phenyl]-2,4-dioxo-5-thiazolidinylidene]methyl]benzoic acid
Show/Hide
|
C18H10F3NO4S
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
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CP0437498
|
3-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
|
C18H10F3NO3S2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
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CP0453164
|
4-((3-(4-fluoro-3-(trifluoromethyl)phenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
|
C18H9F4NO3S2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
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CP0453780
|
17-(2-fluorophenyl)-4,5,12,14-tetramethyl-9-(5-methylfuran-2-yl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-13,15-dione
Show/Hide
|
C28H25FN4O3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
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CP0479242
|
9-(4-hydroxyphenyl)-4,5,12,14-tetramethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-13,15-dione
Show/Hide
|
C29H26N4O3
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0385463
|
9-(3-methoxyphenyl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C28H24N4O3
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
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CP0488928
|
9-(3-methoxyphenyl)-12,14-dimethyl-17-(3-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C29H26N4O3
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0493009
|
9-(4-hydroxyphenyl)-12,14-dimethyl-17-(3-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C28H24N4O3
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0449307
|
9-(4,5-dimethylfuran-2-yl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H24N4O3
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
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CP0529059
|
12,14-dimethyl-9-(5-methylthiophen-2-yl)-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C26H22N4O2S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0479245
|
9-(2-fluoro-3-nitrophenyl)-12,14-dimethyl-17-(3-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C28H22FN5O4
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
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CP0493010
|
12,14-dimethyl-17-(2-methylphenyl)-9-(3-nitrophenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C28H23N5O4
|
1
|
| 1 |
IC50 = 2000 nM
|
|
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CP0500090
|
9-(2-fluorophenyl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H21FN4O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
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CP0502576
|
17-(2-fluorophenyl)-9-(3-methoxyphenyl)-12,14-dimethyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C28H23FN4O3
|
1
|
| 1 |
IC50 = 2000 nM
|
|
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CP0494268
|
12,14-dimethyl-9-(5-methylfuran-2-yl)-8-nitroso-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C26H21N5O4
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
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CP0424285
|
N-[13-[5-chloro-2-(dimethylamino)anilino]-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]-2,2-dimethylpropanamide
Show/Hide
|
C23H28ClN5OS2
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
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CP0555130
|
N-[12-[3-(dimethylamino)anilino]-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-2,2-dimethylpropanamide
Show/Hide
|
C22H27N5OS2
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
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CP0372453
|
9-(3-chlorophenyl)-17-(2-fluorophenyl)-12,14-dimethyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H20ClFN4O2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0385464
|
9-(2-fluorophenyl)-12,14-dimethyl-17-(3-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C28H23FN4O2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0479244
|
12,14-dimethyl-9,17-diphenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H22N4O2
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0497732
|
2-(4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)phenoxy)acetic acid
Show/Hide
|
C19H12F3NO4S2
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0554350
|
N-[13-(5-chloro-2-methoxyanilino)-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]-2-methylbutanamide
Show/Hide
|
C22H25ClN4O2S2
|
1
|
| 1 |
IC50 = 2900 nM
|
|
|
|
CP0385465
|
9-(3-methoxyphenyl)-12,14-dimethyl-17-(2-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C29H26N4O3
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0385466
|
12,14-dimethyl-17-(2-methylphenyl)-9-(3-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C29H26N4O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0529527
|
N-[12-(2-methoxy-5-nitroanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-2,2-dimethylpropanamide
Show/Hide
|
C21H23N5O4S2
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0424287
|
N-[13-(5-chloro-2-methoxyanilino)-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]-2,2-dimethylpropanamide
Show/Hide
|
C22H25ClN4O2S2
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0493008
|
9-(4-hydroxyphenyl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
|
C27H22N4O3
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0424286
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N-[13-(5-chloro-2-methoxyanilino)-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]cyclopropanecarboxamide
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C21H21ClN4O2S2
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1
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| 1 |
IC50 = 4500 nM
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CP0529525
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N-[12-(5-chloro-2-methoxyanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-1,2-oxazole-5-carboxamide
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C20H16ClN5O3S2
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1
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| 1 |
IC50 = 4800 nM
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CP0436942
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3-((3-(4-fluoro-3-(trifluoromethyl)phenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid
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C18H9F4NO3S2
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1
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| 1 |
IC50 = 5000 nM
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CP0453163
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4-((4-oxo-2-thioxo-3-m-tolylthiazolidin-5-ylidene)methyl)benzoic acid
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C18H13NO3S2
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1
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| 1 |
IC50 = 5000 nM
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CP0416911
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12,14-dimethyl-17-(2-methylphenyl)-9-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
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C28H24N4O2
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1
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| 1 |
IC50 = 5000 nM
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CP0463601
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2,2-dimethyl-N-[13-[(3-methylpyridin-2-yl)amino]-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]propanamide
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C21H25N5OS2
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1
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| 1 |
IC50 = 5200 nM
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CP0540041
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N-[13-[3-(dimethylamino)anilino]-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]-2,2-dimethylpropanamide
Show/Hide
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C23H29N5OS2
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1
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| 1 |
IC50 = 5200 nM
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CP0463603
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N-[12-(5-chloro-2-methoxyanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-2-methylpropanamide
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C20H21ClN4O2S2
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1
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| 1 |
IC50 = 5800 nM
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CP0424288
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N-[13-(5-chloro-2-methoxyanilino)-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]-1,2-oxazole-5-carboxamide
Show/Hide
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C21H18ClN5O3S2
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1
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| 1 |
IC50 = 6600 nM
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CP0529524
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N-[12-(5-chloro-2-methoxyanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-2-methylbutanamide
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C21H23ClN4O2S2
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1
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| 1 |
IC50 = 6600 nM
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CP0463602
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N-[12-[5-chloro-2-(dimethylamino)anilino]-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]-2,2-dimethylpropanamide
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C22H26ClN5OS2
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1
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| 1 |
IC50 = 6900 nM
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CP0459621
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4-((3-(2,3-dimethylphenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid
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C19H15NO3S2
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1
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| 1 |
IC50 = 7000 nM
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CP0510204
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5-(3,5-dibromo-4-hydroxybenzylidene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-one
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C17H8Br2F3NO2S2
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1
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| 1 |
IC50 = 7000 nM
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CP0921936
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4-[[2,5-dioxo-1-[3-(trifluoromethyl)phenyl]-3-pyrrolidinyl]thio]-benzoic acid
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C18H12F3NO4S
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1
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| 1 |
IC50 = 7000 nM
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CP0463604
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2,2-dimethyl-N-[12-[(3-methylpyridin-2-yl)amino]-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]propanamide
Show/Hide
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C20H23N5OS2
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1
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| 1 |
IC50 = 7200 nM
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CP0436195
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5-(3,5-dibromo-2,4-dihydroxybenzylidene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-one
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C17H8Br2F3NO3S2
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1
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| 1 |
IC50 = 8000 nM
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CP0385467
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9-(3-fluorophenyl)-12,14-dimethyl-17-(3-methylphenyl)-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
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C28H23FN4O2
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1
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| 1 |
IC50 = 8000 nM
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CP0497731
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4-[[4-Oxo-2-thioxo-3-[2-methyl-3-(trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl] benzoic acid
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C19H12F3NO3S2
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1
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| 1 |
IC50 = 8200 nM
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CP0490634
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methyl 4-[[13-(5-chloro-2-methoxyanilino)-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]amino]-4-oxobutanoate
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C22H23ClN4O4S2
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1
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| 1 |
IC50 = 8300 nM
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CP0459620
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5-(1-Oxido-4-pyridinyl)methylene)-2-thioxo-3-[3-(trifluoromethyl)phenyl]-4-thiazolidinone
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C16H9F3N2O2S2
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1
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| 1 |
IC50 = 8700 nM
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CP0540777
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N-[13-(5-chloro-2-methoxyanilino)-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraen-4-yl]-2-methylpropanamide
Show/Hide
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C21H23ClN4O2S2
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1
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| 1 |
IC50 = 8700 nM
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CP0555131
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methyl 4-[[12-(5-chloro-2-methoxyanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]amino]-4-oxobutanoate
Show/Hide
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C21H21ClN4O4S2
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1
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| 1 |
IC50 = 8800 nM
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CP0426673
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N-[12-(5-chloro-2-methoxyanilino)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraen-4-yl]cyclopropanecarboxamide
Show/Hide
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C20H19ClN4O2S2
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1
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| 1 |
IC50 = 8900 nM
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CP0436944
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4-Oxo-[(3-trifluoromethyl)phenyl]-2-thioxo-N-[4-(carboxy)phenyl]-5-thiazolidinethio carboxamide
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C18H11F3N2O3S3
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1
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| 1 |
IC50 = 9000 nM
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CP0508223
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13-N-(5-chloro-2-methoxyphenyl)-3,12-dithia-5,14-diazatricyclo[9.3.0.02,6]tetradeca-1(11),2(6),4,13-tetraene-4,13-diamine
Show/Hide
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C17H17ClN4OS2
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1
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| 1 |
IC50 = 9200 nM
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CP0436194
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5-(3,4,5-trihydroxybenzylidene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-one
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C17H10F3NO4S2
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1
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| 1 |
IC50 = 11000 nM
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CP0921935
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sodium 3-(4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidine-5-carbothioamido)benzenesulfonate
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C17H10F3N2NaO4S4
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1
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| 1 |
IC50 = 11000 nM
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CP0481419
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12-N-(5-chloro-2-methoxyphenyl)-3,11-dithia-5,13-diazatricyclo[8.3.0.02,6]trideca-1(10),2(6),4,12-tetraene-4,12-diamine
Show/Hide
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C16H15ClN4OS2
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1
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| 1 |
IC50 = 11000 nM
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CP0436941
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4-((4-oxo-2-thioxo-3-(2-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO3S2
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1
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| 1 |
IC50 = 12000 nM
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CP0498047
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3-((4-oxo-2-thioxo-3-(4-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO3S2
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1
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| 1 |
IC50 = 13000 nM
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CP0399199
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4-((3-(3,5-bis(trifluoromethyl)phenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C19H9F6NO3S2
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1
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| 1 |
IC50 = 14000 nM
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CP0437497
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2-hydroxy-5-((4-oxo-2-thioxo-3-(2-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO4S2
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1
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| 1 |
IC50 = 14000 nM
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CP0399200
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2-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO3S2
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1
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| 1 |
IC50 = 15000 nM
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CP0399201
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4-((4-oxo-2-thioxo-3-(4-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO3S2
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1
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| 1 |
IC50 = 15000 nM
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CP0459616
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4-((3-(4-chloro-3-(trifluoromethyl)phenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H9ClF3NO3S2
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1
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| 1 |
IC50 = 15000 nM
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CP0921937
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5-(4-(2H-tetrazol-5-yl)benzylidene)-3-(3-(trifluoromethyl)phenyl)thiazolidine-2,4-dione
Show/Hide
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C18H10F3N5O2S
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1
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| 1 |
IC50 = 17000 nM
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CP0436190
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2-((4-oxo-2-thioxo-3-(2-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO3S2
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1
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| 1 |
IC50 = 18000 nM
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CP0436939
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3-((4-oxo-2-thioxo-3-(2-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO3S2
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1
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| 1 |
IC50 = 19000 nM
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CP0436940
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4-((3-(2-chloro-5-(trifluoromethyl)phenyl)-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H9ClF3NO3S2
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1
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| 1 |
IC50 = 20000 nM
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CP0459617
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2-((4-oxo-2-thioxo-3-(4-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO3S2
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1
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| 1 |
IC50 = 20000 nM
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CP0459619
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5-(4-hydroxybenzylidene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-one
Show/Hide
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C17H10F3NO2S2
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1
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| 1 |
IC50 = 24000 nM
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CP0436192
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2-hydroxy-5-((4-oxo-2-thioxo-3-(4-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid
Show/Hide
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C18H10F3NO4S2
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1
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| 1 |
IC50 = 25000 nM
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CP0498048
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4-Oxo-[(3-trifluoromethyl)phenyl]-2-thioxo-N-[(4-carboxy-3-hydroxy)phenyl]-5-thiazolidinethiocarboxamide
Show/Hide
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C18H11F3N2O4S3
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1
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| 1 |
IC50 = 25000 nM
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CP0436943
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4-[[4-Oxo-2-thioxo-3-[3-(trifluoromethyl)phenyl]-5-thiazolidinyl]methyl]benzoic acid
Show/Hide
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C18H12F3NO3S2
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1
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| 1 |
IC50 = 27000 nM
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CP0858725
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sodium 5-(4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidine-5-carbothioamido)furan-2-sulfonate
Show/Hide
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C15H8F3N2NaO5S4
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1
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| 1 |
IC50 = 27000 nM
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CP0436193
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5-(4-Pyridinylmethylene)-2-thioxo-3-[3-(trifluoromethyl)phenyl]-4-thiazolidinone
Show/Hide
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C16H9F3N2OS2
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1
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| 1 |
IC50 = 28000 nM
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CP0510202
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5-(2,3,4-trihydroxybenzylidene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-one
Show/Hide
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C17H10F3NO4S2
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1
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| 1 |
IC50 = 28000 nM
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CP0554541
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4-(4-(3-(trifluoromethyl)phenyl)thiazol-2-ylamino)benzoic acid
Show/Hide
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C17H11F3N2O2S
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1
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| 1 |
IC50 = 28000 nM
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CP0894412
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sodium 4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzenesulfonate
Show/Hide
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C17H9F3NNaO4S3
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1
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| 1 |
IC50 = 29000 nM
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CP0526230
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2-(3-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)phenoxy)acetic acid
Show/Hide
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C19H12F3NO4S2
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1
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| 1 |
IC50 = 30000 nM
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CP0399203
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2-hydroxy-5-(4-(3-(trifluoromethyl)phenyl)thiazol-2-ylamino)benzoic acid
Show/Hide
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C17H11F3N2O3S
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1
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| 1 |
IC50 = 32000 nM
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CP0858726
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4-(4-chloro-2,5-dioxo-1-(3-(trifluoromethyl)phenyl)-2,5-dihydro-1H-pyrrol-3-ylamino)benzoic acid
Show/Hide
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C18H10ClF3N2O4
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1
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| 1 |
IC50 = 36000 nM
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CP0916639
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sodium (4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzene-1,3-disulfonate
Show/Hide
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C17H8F3NNa2O7S4
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1
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| 1 |
IC50 = 50000 nM
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CP0372452
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9-(4-hydroxy-2-methoxyphenyl)-12,14-dimethyl-17-phenyl-1,8,12,14-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-2,4,6,10,16-pentaene-13,15-dione
Show/Hide
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C28H24N4O4
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1
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| 1 |
IC50 = 100000 nM
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CP0432148
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N-[5-[2-(4-chloroanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-4-nitrobenzamide
Show/Hide
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C20H14ClN5O3S2
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1
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| 1 |
Kd = 800 nM
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CP0437912
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N-[5-[2-(2-ethoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Show/Hide
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C20H24N4O2S2
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1
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| 1 |
Kd = 800 nM
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CP0233409
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N-[5-[2-(2,5-dimethoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]heptanamide
Show/Hide
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C22H28N4O3S2
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1
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| 1 |
Kd = 1100 nM
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CP0294667
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N-[5-[2-(2-methoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide
Show/Hide
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C19H22N4O2S2
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1
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| 1 |
Kd = 1100 nM
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CP0386317
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4-chloro-N-[4-methyl-5-[2-(4-methylanilino)-1,3-thiazol-4-yl]-1,3-thiazol-2-yl]benzamide
Show/Hide
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C21H17ClN4OS2
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1
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| 1 |
Kd = 1100 nM
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CP0458172
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4-chloro-N-[5-[2-(4-chloroanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide
Show/Hide
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C20H14Cl2N4OS2
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1
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| 1 |
Kd = 1100 nM
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CP0515142
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4-chloro-N-[5-[2-(2,5-dimethoxyanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]benzamide
Show/Hide
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C22H19ClN4O3S2
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1
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| 1 |
Kd = 1100 nM
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