Brief Information of the Compound and Protein
Compound Name
(8-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-[1-methyl-5-(trifluoromethyl)pyrazol-3-yl]methanone
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Canonical SMILES
COc1ccc2[nH]c3CCN(Cc3c2c1)C(=O)c1cc(n(C)n1)C(F)(F)F
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Compound Formula C18H17F3N4O2
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 7100 nM
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