Brief Information of the Compound and Protein
Compound Name
[5-(trifluoromethyl)-1H-pyrazol-3-yl]-[8-(trifluoromethyl)-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl]methanone
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Canonical SMILES
FC(F)(F)c1cc(n[nH]1)C(=O)N1CCc2[nH]c3ccc(cc3c2C1)C(F)(F)F
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Compound Formula C17H12F6N4O
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000259 FRT Rattus norvegicus (Rat)  1
1
EC50 = 440 nM
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