Brief Information of the Compound and Protein
Compound Name
 Compound Info 
MLS000561583
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 PubChem ID
CID: 11958611
SID: 57581604
Canonical SMILES
COc1ccc(Cl)cc1Nc1nc(cs1)-c1sc(NC(=O)C(C)(C)C)nc1C
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Compound Formula C19H21ClN4O2S2
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o-
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 707.95 nM
   TI
   LI
   LO
   TS
CL000259 FRT
 Cell Line Info 
Rattus norvegicus (Rat)  2
1
EC50 = 700 nM
   TI
   LI
   LO
   TS
2
Kd = 700 nM
   TI
   LI
   LO
   TS